Wounding the stroma: Docetaxel's role in dormant breast cancer escape.

PLoS Biol

Biomedical and Molecular Sciences, Queen's University, Kingston, Canada.

Published: September 2023

The mechanistic underpinnings of breast cancer recurrence following periods of dormancy are largely undetermined. A new study in PLOS Biology reveals that docetaxel-induced injury of tumour stromal cells stimulates the release of cytokines that support dormancy escape of breast cancer cells.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10499231PMC
http://dx.doi.org/10.1371/journal.pbio.3002297DOI Listing

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