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Comparative study of the anthelmintic activity of ethanolic and aqueous extracts of Atriplex halimus, the anti-echinococcal plant used in Algeria.

Vet Parasitol Reg Stud Reports

September 2024

Service of Surgery of the Child and the Adolescent CHU of Setif, Ferhat Abbas University, Setif 1, Algeria; Laboratory of Applied Pediatric Surgery, CHU of Setif, Ferhat Abbas University, Setif 1, Setif, Algeria.

Article Synopsis
  • - Cystic echinococcosis (CE) poses a significant health risk in Algeria, with surgery being the main treatment but facing complications like recurrence from protoscoleces spread during operations.
  • - This study evaluated the scolicidal effects of Atriplex halimus extracts (both ethanolic and aqueous) by analyzing their phytochemical content and antioxidant activity, finding notable differences in phenolic and flavonoid levels.
  • - The results indicated that both extracts showed strong scolicidal effects at specific concentrations and times, suggesting that Atriplex halimus could be a promising natural option to enhance CE surgical outcomes.
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The present investigation aims to develop and evaluate silver nanoparticles (AgNP) synthesized through environmentally friendly methods and to assess their effectiveness against hydatid cysts through in vitro, ex vivo, and in vivo experiments. The green synthesis of ANP was accomplished using the precipitation technique with Astragalus spinosus extract. The in vitro protoscolicidal effects of ANP were evaluated on hydatid cyst protoscoleces (PTS) through eosin exclusion test.

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Cystic echinococcosis (CE) is a significant global public health concern, particularly in regions where livestock rearing is prevalent. Despite its impact on morbidity and mortality, CE has received insufficient attention compared to other neglected tropical diseases. The complexities in CE management arise from challenges in early detection, effective treatment, and parasite eradication.

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This current , , and research aims to evaluate and analyze the linalool-zinc oxide nanocomposite (Lin-ZNP) for treating cystic echinococcosis. Lin-ZNP was synthesized using an ethanolic solution of polyvinyl alcohol. The protoscolicidal effects of Lin-ZNP were tested on hydatid cyst protoscoleces (PTS) in both and by eosin exclusion test.

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Hypochlorous Acid: A Novel Agent Against Protoscoleces.

Infect Dis Clin Microbiol

June 2023

Department of Public Health, Çanakkale Public Health Laboratory, Ministery of Health Çanakkale, Turkey.

Objective: We aimed to determine the scolicidal effect of hypochlorous acid and its efficiency at different concentrations.

Materials And Methods: We tested the effectiveness of hypochlorous acid in-vitro on sterile gauze at different concentrations in test tubes. In addition, we compared its effectiveness with the scolicidal activity of other agents, povidone-iodine 10% and chlorhexidine-gluconate 0.

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