AI Article Synopsis
- Uterine fibroids are common benign tumors in the uterus, but their removal (myomectomy) may not improve IVF success in women with non-cavity-distorting intramural fibroids.
- A study at Acibadem Maslak Hospital analyzed 128 women who underwent IVF, comparing those who had myomectomy to those who did not, all of whom experienced at least two IVF failures.
- Results showed no significant difference in IVF and pregnancy outcomes between the two groups, indicating that myomectomy does not substantially influence pregnancy or live birth rates.
Article Abstract
Background: Uterine fibroids are the most common benign smooth muscle tumors of the uterus. However, there is no consensus on whether myomectomy improves IVF success in women with non-cavity-distorting intramural fibroids. The aim of this study was to compare the IVF and pregnancy outcomes of women who had non-cavity-distorting intramural fibroids and underwent myomectomy vs women who had intramural fibroids, but did not undergo myomectomy.
Methods: A retrospective cohort study at Acibadem Maslak Hospital, IVF Center, between 2019 and 2020. Data of 128 women aged between 25 and 43 years who have at least 2 intramural non-cavity-distorting fibroids of 2-6 cm in size were used. All patients had at least two IVF failure. The intervention group comprised women who decided to proceed to myomectomy before IVF (Group 1, = 56). The control group was established women with intramural fibroids who reject myomectomy (Group 2, = 71).
Results: In regard to IVF result parameters and perinatal outcomes, there was no statistically significant difference between the two groups. Between study groups, there were no statistically significant differences in the perinatal outcomes. Myomectomy surgery did not increase miscarriage and biochemical pregnancy rate (odds ratio (OR) 0.9; 95% confidence interval (CI) 2.8-3.7).
Conclusion: Myomectomy does not impact on pregnancy or live birth rates substantially, according to the results of this study.
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|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10492715 | PMC |
| http://dx.doi.org/10.1007/s13224-023-01750-2 | DOI Listing |
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