AI Article Synopsis
- Breast implant-associated anaplastic large cell lymphoma (BIA-ALCL) is a rare cancer that can develop in women with breast implants, typically around eight years post-surgery.
- Over 700 cases have been documented globally since 1997, with a focus on cases associated with Allergan's recalled textured implants, prompting a U.S. registry for better understanding.
- Although BIA-ALCL is uncommon, it is crucial to consider it when a woman with a textured implant presents with breast swelling and fluid accumulation; fortunately, most cases are treatable with complete surgical removal.
Article Abstract
Breast implant-associated anaplastic large cell lymphoma (BIA-ALCL) is a rare cancer found in women with breast implants, occurring approximately eight years after their placement. Since the initial case report of BIA-ALCL in 1997, over 700 cases have been described worldwide and there is now a registry of cases diagnosed in the United States to help learn more about this disease process and prognosis. The majority of cases have been associated with Allergan's textured implants which have been recalled. As this disease is relatively rare with only 1,130 cases described worldwide, it is important to keep BIA-ALCL in mind in the differential diagnosis of a woman presenting with breast swelling and peri-implant fluid collection in the setting of having a textured implant. Outcomes for women with BIA-ALCL are favorable, as most disease is contained within the peri-implant capsule. Thus, complete surgical resection is often curative. Here, we report the case of a 40-year-old woman with BIA-ALCL who presented with unilateral breast swelling in the peripartum period.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10493074 | PMC |
| http://dx.doi.org/10.7759/cureus.43334 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Breast Implant Surgery: The Importance of Informed Health Care Decisions and Outcome Monitoring.
Plast Aesthet Nurs (Phila)
December 2024
Jessica Prothe, BSN, RN, is a Graduate Nursing Student at Northern Illinois University, DeKalb, Illinois.
Breast implant surgery is a popular, globally performed, and frequently requested cosmetic and reconstructive surgical procedure. Breast implant surgery can cause implant-associated systemic symptoms and types of implant-associated cancers, so it is vital to monitor patient outcomes. Most patients who undergo breast implant surgery do not experience health problems.
View Article and Find Full Text PDFPeri-Implant Enhancement of the Breast: Imaging Features, Significance, and Management Strategies.
J Breast Imaging
December 2024
Division of Plastic and Reconstructive Surgery, Mayo Clinic in Florida, Jacksonville, FL, USA.
Objective: Peri-implant enhancement can be seen on contrast-enhanced breast MRI, but its association with malignancy has not been described, leading to considerable variability in assessment and recommendations by radiologists. This study evaluated imaging features, management, and outcomes of implant-related enhancement.
Methods: This multisite IRB-approved retrospective review queried all breast MRI reports for keywords describing peri-implant enhancement, fluid, and/or masses (plus synonymous descriptions) and implant-associated malignancies, with subsequent imaging and chart review.
Enhancement to effusion: Breast implant-associated anaplastic large cell lymphoma.
J Cardiol Cases
December 2024
Department of Internal Medicine, University of Texas at Austin Dell Medical School, Austin, TX, USA.
Unlabelled: This case is a rare presentation of breast implant-associated anaplastic large cell lymphoma (BIA-ALCL), where malignant pericardial effusion (MPE) served as the primary manifestation. A 58-year-old woman, post-breast implant removal, presented with pleuritic chest pain, fever, and chills. Clinical evaluation revealed jugular venous distention, muffled heart sounds, and hemodynamic instability.
View Article and Find Full Text PDFEmerging Non-Breast Implant-Associated Lymphomas: A Systematic Review.
Cancers (Basel)
December 2024
PROMISE Department, University of Palermo, 90127 Palermo, Italy.
Medical devices used for functional or esthetic purposes improve health and quality of life; however, they are not risk-free. Anaplastic large-cell lymphoma (ALCL), associated with breast implants, is a well-known and recognized distinct lymphoma entity. More recently, additional lymphomas have been reported in relation to prosthesis other than breast implants, as these allow the pericyte to develop into a clone that undergoes a maturation process, progressing toward full malignancy.
View Article and Find Full Text PDFThe impact of Breast Implant-Associated Anaplastic Large Cell Lymphoma on breast implant surgery: A European survey-based study.
J Plast Reconstr Aesthet Surg
November 2024
Faculty of Medicine and Psychology, Sapienza University of Rome, Department of Neuroscience, Mental Health and Sense Organs (NESMOS), Sant'Andrea Hospital, Via di Grottarossa 1035-1039, 00189 Rome, Italy.
Background: Over the 27 years following the first report of Breast Implant-Associated Anaplastic Large Cell Lymphoma (BIA-ALCL), significant changes have been made in breast implant surgery trends. This study aimed to determine breast implant selection changes among European plastic surgeons.
Methods: The European Association of Plastic Surgeons (EURAPS) promoted a digital survey to 31 national plastic surgery societies across Europe, which spread it to their members.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!