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Skin Physiological Parameters and Their Association with Severe Atopic Dermatitis in Mongolian Children.
J Clin Med
December 2024
Department of Physiology, School of Biomedicine, Mongolian National University of Medical Sciences, Ulaanbaatar 14210, Mongolia.
: Atopic dermatitis (AD) is a chronic skin condition that weakens the skin barrier, leading to increased trans-epidermal water loss and reduced skin moisture. Understanding how these changes in the skin barrier relate to AD severity in Mongolian children may offer insights that could apply to other regions facing similar environmental challenges. : A cross-sectional study was conducted at the National Dermatology Center of Mongolia, involving 103 children with AD.
View Article and Find Full Text PDFFecal Calprotectin Determination in a Cohort of Children with Cow's Milk Allergy.
Nutrients
January 2025
Independent Researcher, 00100 Rome, Italy.
Cow's milk allergy (CMA) is the most common food allergy among children. An oral food challenge (OFC) remains a mainstay of the diagnosis of CMA, especially for the non-IgE-mediated type; however, this test can be risky and time-consuming. Hence, there is a need to identify biomarkers.
View Article and Find Full Text PDFFood Protein-Induced Allergic Proctocolitis: Real-World Experience from an Italian Cohort.
Nutrients
December 2024
Allergy Unit, Meyer Children's Hospital IRCCS, 50139 Florence, Italy.
: Food protein-induced allergic proctocolitis (FPIAP) is a non-IgE-mediated food allergy, usually presenting as bloody stools in breastfed, well-appearing, and regularly growing infants. The aim of our study was to describe the clinical features of Italian infants affected by FPIAP and their management and natural history in a real-life setting. : A retrospective, observational study was performed at two tertiary pediatric hospitals (Florence and Trieste), including FPIAP-diagnosed infants between 2012 and 2022.
View Article and Find Full Text PDFSynergistic Synbiotic-Containing and Fructo-Oligosaccharide Alleviate the Allergenicity of Mice Induced by Soy Protein.
Foods
January 2025
State Key Laboratory of Food Science and Resources, Nanchang University, Nanjing Dong Lu 235, Nanchang 330047, China.
Prebiotics and probiotics have key roles in the intervention and treatment of food allergies. This study assesses the effect of synergistic fructo-oligosaccharide (Lp-FOS) intervention using an allergic mouse model induced by soy protein. The results showed that Lp synergistic FOS significantly decreased clinical allergy scores, inhibited specific antibodies (IgE, IgG, and IgG1), IL-4, IL-6, and IL-17A levels, and increased IFN-γ and IL-10 levels.
View Article and Find Full Text PDFDecoding Pediatric Laryngopharyngeal Reflux: Unraveling Symptoms Through Multichannel Intraluminal Impedance and pH Insights.
Diagnostics (Basel)
December 2024
Referral Center for Pediatric Gastroenterology and Nutrition, Children's Hospital Zagreb, 10000 Zagreb, Croatia.
The relationship between symptoms of laryngopharyngeal reflux (LPR) and objective reflux measurements obtained through multichannel intraluminal impedance-pH (MII-pH) monitoring remains unclear. The aim of this study was to investigate the relationship between LPR symptoms and objective reflux episodes and possible associations between fibreoptic ENT findings, eosinophil counts, and serum IgE levels with reflux episodes detected by MII-pH. In this prospective study, MII-pH monitoring, fiberoptic laryngoscopy, nasal swabs for eosinophils, total serum IgE levels, and symptom assessment (Reflux Symptom Index, RSI) were performed in all children with suspected LPR.
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