Industrial biotechnology is an integrated technology that utilizes biochemical reactions and biofunctions to achieve substance synthesis and energy conversion. The development of industrial biotechnology supports a green, efficient, and new route for manufacturing of chemicals using renewable raw materials. It is expected to bring a fundamental shift in industrial manufacturing and a change in economic growth mode. Industrial biotechnology is an important strategic technology supporting the sustainable development of social economy and has become a focus of global competition on science and technology. Based on an elaboration of industrial biotechnology's deep integration in bioeconomy, this paper summarized the current situation and developmental trends of industrial biotechnology and biomanufacturing industry in China. Gaps between developed countries and China as well as key areas for biotechnology development were proposed, followed by identifying tasks and directions for future development of biomanufacturing industry.

Download full-text PDF

Source
http://dx.doi.org/10.13345/j.cjb.220782DOI Listing

Publication Analysis

Top Keywords

industrial biotechnology
20
current situation
8
situation developmental
8
developmental trends
8
trends industrial
8
biotechnology biomanufacturing
8
biomanufacturing industry
8
industrial
7
biotechnology
6
[the current
4

Similar Publications

Selenium is an essential element with various industrial and medical applications, hence the current considerable attention towards the genesis and utilization of SeNPs. SeNPs and other nanoparticles could be achieved via physical and chemical methods, but these methods would not only require expensive equipment and specific reagents but are also not always environment friendly. Biogenesis of SeNPs could therefore be considered as a less troublesome alternative, which opens an excellent window to the selenium and nanoparticles' world.

View Article and Find Full Text PDF

Construction of Escherichia coli cell factory for efficient synthesis of indigo.

Chembiochem

January 2025

Jiangnan University, State Key Laboratory of Food Science and Technology, 1800 Lihu Road, Wuxi, China, 214122, Wuxi, CHINA.

Indigo is widely used in dyes, medicines and semiconductors materials due to its excellent dyeing efficiency, antibacterial, antiviral, anticancer, anti-corrosion, and thermostability properties. Here, a biosynthetic pathway for indigo was designed, integrating two enzymes (EcTnaA, MaFMO) into a higher L-tryptophan-producing the strain Escherichia coli TRP. However, the lower catalytic activity of MaFMO was a bottleneck for increasing indigo titers.

View Article and Find Full Text PDF

A parallel bioreactor strategy to rapidly determine growth-coupling relationships for bioproduction: a mevalonate case study.

Biotechnol Biofuels Bioprod

January 2025

Manchester Institute of Biotechnology, The University of Manchester, 131 Princess Street, Manchester, M1 7DN, UK.

Background: The climate crisis and depleting fossil fuel reserves have led to a drive for 'green' alternatives to the way we manufacture chemicals, and the formation of a bioeconomy that reduces our reliance on petrochemical-based feedstocks. Advances in Synthetic biology have provided the opportunity to engineer micro-organisms to produce compounds from renewable feedstocks, which could play a role in replacing traditional, petrochemical based, manufacturing routes. However, there are few examples of bio-manufactured products achieving commercialisation.

View Article and Find Full Text PDF

Inducible engineering precursor metabolic flux for synthesizing hyaluronic acid of customized molecular weight in Streptococcus zooepidemicus.

Microb Cell Fact

January 2025

MOE Key Laboratory of Industrial Fermentation Microbiology, College of Biotechnology, Tianjin University of Science and Technology, Tianjin, 300457, P. R. China.

Background: Hyaluronic acid (HA) is extensively employed in various fields such as medicine, cosmetics, food, etc. The molecular weight (MW) of HA is crucial for its biological functions. Streptococcus zooepidemicus, a prominent HA industrial producer, naturally synthetizes HA with high MW.

View Article and Find Full Text PDF

This study investigates a nanoparticle-based doxycycline (DOX) delivery system targeting cervical cancer cells via the CD44 receptor. Molecular docking revealed a strong binding affinity between hyaluronic acid (HA) and CD44 (binding energy: -7.2 kJ/mol).

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!