AI Article Synopsis

  • Invasive lobular carcinoma (ILC) is the second most common type of invasive breast cancer and can have atypical metastatic patterns, including gastric involvement.
  • A 62-year-old woman showed signs of gastric outlet obstruction due to a gastric mass, which was initially thought to be primary adenocarcinoma based on endoscopic findings.
  • F-FDG PET/CT scans revealed both gastric and axillary metastases, prompting the need to differentiate between primary gastric cancer and metastatic breast ILC, as treatment options differ significantly.

Article Abstract

Invasive lobular carcinoma (ILC) is the second most common subtype of invasive breast cancer and sometimes presents with an unusual metastatic pattern. Its gastric metastasis is difficult to differentiate from primary adenocarcinoma. This report presents a case of breast ILC for which the initial presentation was gastric metastasis. A 62-y-old woman presented with gastric outlet obstruction secondary to a gastric mass that had been diagnosed on upper gastrointestinal endoscopy and biopsy. The patient had been referred for F-FDG PET/CT for staging. The baseline F-FDG PET/CT scan demonstrated extensive axillary nodal and gastric metastases with a breast mass, which raised suspicion of a primary breast carcinoma. Distinguishing primary gastric adenocarcinoma from metastatic breast ILC is essential, considering that the 2 diagnoses lead to divergent treatments. Therefore, this entity needs to be considered in the differential diagnosis in clinical practice.

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http://dx.doi.org/10.2967/jnmt.123.266035DOI Listing

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