AI Article Synopsis
- This study aimed to investigate how common polycystic ovarian syndrome (PCOS) and hyperandrogenism are in adolescent transmasculine patients seeking gender-affirming care at a tertiary center.
- The findings indicated that 23.8% of these patients had PCOS, with those affected showing higher levels of androgens and body mass indexes compared to those without the condition.
- The study concludes that PCOS may be more prevalent in transmasculine patients than in the general population, highlighting the importance of thorough counseling and screening for health risks associated with PCOS in this group.
Article Abstract
Study Objective: To determine the incidence of polycystic ovarian syndrome (PCOS) and hyperandrogenism among adolescent transmasculine patients presenting to a tertiary care referral center for gender-affirming care METHODS: This was a retrospective study of adolescent transmasculine patients presenting to Cleveland Clinic for gender-affirming hormone therapy. The diagnostic criteria were adolescent-specific as defined by the international evidence-based guideline for PCOS management and included oligomenorrhea and/or anovulation with clinical and/or biochemical hyperandrogenism after exclusion of other androgen excess disorders.
Results: The described transgender population had a prevalence of PCOS of 23.8%. The transmasculine patients who met the criteria for PCOS had both higher levels of androgens and higher body mass indexes when compared with the patients without PCOS. Additionally, the patients with PCOS had higher rates of dyslipidemia.
Conclusion: The prevalence of PCOS among transmasculine patients may be higher compared with the general population. Transmasculine patients with PCOS should be counseled regarding the long-term health implications associated with PCOS and screened appropriately to minimize risks.
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| http://dx.doi.org/10.1016/j.jpag.2023.09.003 | DOI Listing |
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