Epidemiology of hidradenitis suppurativa.

Clin Dermatol

School of Medicine University of Zagreb, University Hospital Centre Zagreb, Department of Dermatology and Venereology, European Reference Network (ERN) - Skin, Zagreb, Croatia. Electronic address:

Published: December 2023

AI Article Synopsis

  • * The condition is more common in women than men in North America and Europe, while the opposite is true in South Korea and Japan, with the disease typically appearing in individuals aged 18-29.
  • * Studies suggest a link between HS and factors like smoking, obesity, and mental health issues, but more research is needed to clarify these relationships and understand discrepancies in HS prevalence across different populations.

Article Abstract

Hidradenitis suppurativa (HS) is a chronic, inflammatory, recurrent skin disease affecting hair follicles in predominantly intertriginous areas, characterized by deep, painful nodules and abscesses, fistulas, sinus tracts, and scarring. The estimated global prevalence of HS is highly variable, as revealed in a growing body of published literature, and ranges from 0.053% to 4.1%. In North American and European patients, HS is three times more common in women than men, whereas in South Korea and Japan, male predominance is found. The disease most frequently manifests itself between the ages of 18 and 29. Numerous published studies have reported the association between smoking, obesity, and HS, although there are limitations in confirming the causal relationship due to the retrospective design of the available studies. Case-control studies have frequently evaluated the association between HS, metabolic syndrome, and other systemic comorbidities. Due to increased mental health problems, a higher risk of suicide in patients with HS has been reported. We provide up-to-date evidence about the epidemiology, genetic and environmental risk factors, comorbidities, and quality of life of patients with HS. The divergence in HS frequency, possibly due to differences in populations and methodologies, remains to be explained in future worldwide studies.

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Source
http://dx.doi.org/10.1016/j.clindermatol.2023.08.020DOI Listing

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