AI Article Synopsis

  • The study explores a new device called hANDY-i, designed to help locate parathyroid glands during a minimally invasive thyroid surgery called transoral endoscopic thyroidectomy vestibular approach (TOETVA).
  • The hANDY-i uses advanced imaging technology to provide real-time views of both normal and near-infrared fluorescence of the parathyroid glands, assisting surgeons during the procedure.
  • Initial results show that this device successfully identified parathyroid glands in a cadaver and two patients, indicating potential benefits for preventing complications, but more research is needed to confirm its effectiveness in reducing postoperative issues.

Article Abstract

Background: Treatment options for thyroid pathologies have expanded to include scarless and remote access methods such as the transoral endoscopic thyroidectomy vestibular approach (TOETVA). Currently, no standardized methods exist for locating parathyroid glands (PGs) in patients undergoing TOETVA, which can lead to parathyroid injury and subsequent hypocalcemia. This early feasibility study describes and evaluates the hANDY-i endoscopic attachment for detecting PGs in transoral thyroidectomy.

Methods: We used a prototype parathyroid autofluorescence imager (hANDY-i) that was mounted to a 10-mm 0-degree endoscope. The device delivers a split screen view of Red-green-blue (RGB) and near-infrared autofluorescence (NIRAF) which allows for simultaneous anatomical localization and fluorescence visualization of PGs during endoscopic thyroid dissection.

Results: One cadaveric case and two patient cases were included in this study. The endoscopic hANDY-i imaging system successfully visualized PGs during all procedures.

Conclusion: The ability to leverage parathyroid autofluorescence during TOETVA may lead to improved PG localization and preservation. Further human studies are needed to assess its effect on postoperative hypocalcemia and hypoparathyroidism.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10484600PMC
http://dx.doi.org/10.3389/fendo.2023.1233956DOI Listing

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