Excipient Lung Disease in a Patient with Preexisting Chronic Thromboembolic Disease.

Radiol Cardiothorac Imaging

From the Department of Radiology, Jewish General Hospital, 3755 ch de la Côte-Sainte-Catherine, Montreal, QC, Canada H3T 1E2 (G.G.); and Department of Radiology, National Jewish Health, Denver, Colo (S.J.K.).

Published: August 2023

Excipient lung disease is an uncommon condition that occurs when crushed oral tablets are injected intravenously and cause pulmonary hypertension. Diagnosis requires a high degree of clinical suspicion and recognition of characteristic imaging findings. The authors present a previously unreported combination of findings in a patient with excipient lung disease and preexisting chronic thromboembolic disease. A pattern of diffuse centrilobular nodules with sparing of lung segments with chronically occluded pulmonary arteries was highly suggestive of the diagnosis and indicated a vascular cause. Pathologic specimen obtained at the time of pulmonary thromboendarterectomy helped confirm the clinically suspected entity. Pulmonary Arteries, Embolism/Thrombosis, Foreign Bodies, Lung Supplemental material is available for this article. © RSNA, 2023.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10483241PMC
http://dx.doi.org/10.1148/ryct.230059DOI Listing

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