Cellular angiofibromas (CAFs) are infrequent and benign soft-tissue tumors that primarily affect the genitourinary region in both genders. The authors report the case of a 71-year-old male patient who exhibited progressively increasing swelling in both testicles, with greater prominence noted on the left side. Initial findings from physical examination and scrotal ultrasound indicated the possibility of bilateral hydrocele, so the patient was recommended surgical intervention of the left more prominent side. Intraoperatively, a left paratesticular mass was identified and subsequently excised. Histopathological analysis confirmed the diagnosis of cellular angiofibroma. Surgeons should be cognizant of this tumor type to optimize treatment strategies, as local excision demonstrates a potential to preserve the testicle and yield favorable outcomes. Although occurrences of local recurrence are extremely rare, long-term follow-up is imperative.
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http://dx.doi.org/10.7759/cureus.43124 | DOI Listing |
Cureus
October 2024
Oncology, Pontifícia Universidade Católica Do Rio Grande Do Sul, Porto Alegre, BRA.
Rhabdomyosarcomas, malignant mesenchymal tumors of skeletal striated muscle tissue cells, are usually rare in adults. However, when they occur in this population, the prognosis is usually poor, especially if the condition is associated with molecular factors such as the PAX3-FOXO1 fusion. Here, We report a case of paratesticular alveolar rhabdomyosarcoma in an adult patient who initially complained of increased scrotal volume for two years and presented with a PAX3-FOXO1 fusion.
View Article and Find Full Text PDFAm J Surg Pathol
January 2025
Departments of Pathology, CORE Diagnostics and CORE Group of Reference Laboratories, India.
Urol Case Rep
November 2024
Wright State University Boonshoft School of Medicine, Division of Urology, Dayton, OH, USA.
Scrotal cellular angiofibroma (CAF) is a rare, benign, soft-tissue paratesticular tumor that has been sporadically reported previously. We present a case of a 55-year old male with a scrotal mass ultimately diagnosed with scrotal CAF. Immunohistochemical analysis stained positively for desmin, CD34, and estrogen receptor.
View Article and Find Full Text PDFExp Cell Res
October 2024
Department of Neurosciences, Biomedicine and Movement Sciences, Biochemistry Section, University of Verona, Verona, Italy. Electronic address:
Testicular descent is a crucial event in male sexual development, and alterations in this process during gestation can lead to reduced fertility in adulthood. Cryptorchidism, i.e.
View Article and Find Full Text PDFRadiol Case Rep
October 2024
Department of Radiology, The Royal Free Hospital, NHS Foundation Trust, London, United Kingdom.
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