Determining the measurement accuracy in assessing the progress of wound healing.

Postepy Dermatol Alergol

Institute of Physiotherapy and Health Sciences, Electromyography and Pelvic Floor Muscles Laboratory, Department of Physical Medicine, The Jerzy Kukuczka Academy of Physical Education, Katowice, Poland.

Published: August 2023

Introduction: Wound management is a challenge in terms of the way, duration and cost of treatment both for the patient and health providers. The healing of skin wounds is a highly multi-step coordinated process. Objective monitoring of treatment at every stage is necessary to assess the applied therapy.

Aim: To show the possibility of using the AutoCad software (ACS) as a tool with a slight measurement error for accurate measurement of the venous leg ulcers on the lower limbs.

Material And Methods: To determine the error of the measurement method Circle Templates For Drafting for four different sizes were used as ulcer models. Seventy-six wounds of various sizes from patients with venous leg ulcers (VLUs) were photographed and outlined with a marker on a transparent foil. The wounds were measured both using ACS and digital planimetry with C-Geo software (CGS). Data were analysed using Wilcoxon test, intraclass correlation coefficient (ICC) and Bland-Altman analysis.

Results: The mean relative error of the surface wound model area measured by the ACS was 0.30 ±0.31% (range: 0.004-1.25) and a median of 0.18%. Areas and perimeters measured with ACS were higher than areas and perimeters measured with CGS, and the difference was statistically significant.

Conclusions: The analysis of the wound images obtained in the ACS showed a very high potential of the software in terms of the accuracy of the analysed areas, which significantly increases the possibility of the analysis and reduces the measurement error in relation to planimetry using a digital digitizer.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10485759PMC
http://dx.doi.org/10.5114/ada.2023.129326DOI Listing

Publication Analysis

Top Keywords

measured acs
12
measurement error
8
venous leg
8
leg ulcers
8
areas perimeters
8
perimeters measured
8
acs
5
determining measurement
4
measurement accuracy
4
accuracy assessing
4

Similar Publications

Small molecule degraders such as PROteolysis TArgeting Chimeras (PROTACs) and molecular glues are new modalities for drug development and important tools for target validation. When appropriately optimized, both modalities lead to proteasomal degradation of the protein of interest (POI). Due to the complexity of the induced multistep degradation process, controls for degrader evaluation are critical and commonly used in the literature.

View Article and Find Full Text PDF

Enhancing Carbon Monoxide Tolerance in Low-Temperature PEM Fuel Cells through Carbon Nitride Surface Modification.

ACS Appl Mater Interfaces

January 2025

State Key Laboratory of Physical Chemistry of Solid Surfaces, College of Chemistry and Chemical Engineering, Xiamen University, Xiamen 361005, China.

Article Synopsis
  • Low-temperature proton exchange membrane fuel cells (PEMFCs) need very pure hydrogen gas because they are highly sensitive to carbon monoxide (CO) contamination.
  • A surface modification technique was developed, applying a 0.5-0.91 nm amorphous carbon nitride layer on PtRu/C substrates, improving hydrogen transport while blocking CO diffusion.
  • This modification significantly reduces CO adsorption, maintaining stable catalyst operation for over 20 hours even with high CO levels (1000 ppm), and allows stable performance in PEMFCs with CO concentrations up to 10 ppm, surpassing the standard limit of 0.2 ppm.
View Article and Find Full Text PDF

Recent research shows a significant link between race-ethnicity and income concentration and premature death rates in the U.S. However, most studies focus on Black-White residential concentration, overlooking racial-ethnic diversity.

View Article and Find Full Text PDF

Background: The extracellular amyloid plaques, one of the pathological hallmarks of Alzheimers Disease (AD), are frequently also observed in the cortex of cognitively unimpaired subjects or as co-pathology in other neurodegenerative diseases. Progressive deposition of fibrillar amyloid-β (Aβ) as amyloid plaques for two decades prior disease onset leads to extensive isomerization of Aβ N-terminus. Quantifying the extent of isomerized Aβ can be provide insight into the different stages of amyloidosis in the brain.

View Article and Find Full Text PDF

Portable sensor technologies are indispensable in personalized healthcare and environmental monitoring as they enable the continuous tracking of key analytes. Human sweat contains valuable physiological information, and previously developed noninvasive sweat-based sensors have effectively monitored single or multiple biomarkers. By successfully detecting biochemicals in sweat, portable sensors could also significantly broaden their application scope, encompassing non-biological fluids commonly encountered in daily life, such as mineral water.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!