Case Report: Atypical presentation of non-functional gonadotropinoma.

F1000Res

Endocrinology & diabetes Department, Swansea University, Swansea, Wales, UK.

Published: September 2023

Gonadotropinoma is the most common non-functional pituitary adenoma comprising 10%-30% of all pituitary adenomas. They are benign slow-growing tumours originating from adenohypophysis and rarely become malignant. Its presentation can be atypical, such as visual disturbance, and most patients presenting to an ophthalmologist for visual correction are eventually found to have a field defect. Here, we report a case of a 59-year-old patient who presented with a left-sided visual disturbance, which progressed over the years due to a left temporal hemianopia. The patient was referred to us by an ophthalmologist and was diagnosed with a giant non-functional gonadotropinoma. The patient was surgically treated. Postoperative follow-up magnetic resonance imaging after 3 months showed near complete resection of the tumour.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10483175PMC
http://dx.doi.org/10.12688/f1000research.133438.1DOI Listing

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Case Report: Atypical presentation of non-functional gonadotropinoma.

F1000Res

September 2023

Endocrinology & diabetes Department, Swansea University, Swansea, Wales, UK.

Gonadotropinoma is the most common non-functional pituitary adenoma comprising 10%-30% of all pituitary adenomas. They are benign slow-growing tumours originating from adenohypophysis and rarely become malignant. Its presentation can be atypical, such as visual disturbance, and most patients presenting to an ophthalmologist for visual correction are eventually found to have a field defect.

View Article and Find Full Text PDF

Clinically non-functional pituitary adenomas are often derived from gonadotropin producing cells. However, gonadotropinomas causing elevated serum levels of follicle-stimulating hormone (FSH) and clinical signs of FSH hypersecretion are very rarely described. Our patient, a 56-year-old man, was referred to our clinic with signs of hypogonadism.

View Article and Find Full Text PDF

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