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Background: Distal radius fractures (DRFs) are some of the most common injuries suffered by the elderly; however, there are varied opinions on management. As there is limited research on patient factors affecting functional outcomes in conservatively managed patients with DRFs, this study aimed to find predictive factors for functional outcomes in such patients.
Methods: Patients with DRFs satisfying the inclusion criteria were managed with closed reduction and slab followed by cast application.
Measuring associations between the food environment and dietary habits: comparing the proportion and density of food outlets.
BMC Public Health
December 2024
Center for Clinical Research and Prevention, Copenhagen University Hospital - Bispebjerg and Frederiksberg, Copenhagen, Denmark.
Background: The food environment plays a crucial role in shaping our dietary choices and overall health. Spatial measures provide distinct perspectives on the physical food environment and its impact on diet. While proportion measures are theoretically considered to provide a more accurate representation of the overall physical food environment than density measures, it is important to recognize that the association between food environments and diet can vary depending on the context.
View Article and Find Full Text PDFNon-HDL Cholesterol May Be Preferred over Apolipoprotein B-100 for Risk Assessment when Evaluated by Receiver Operator Characteristic Curve Analysis.
J Appl Lab Med
December 2024
Department of Medicine, Section of Endocrinology, Metabolism and Diabetes, University of Louisville, Louisville, KY, United States.
Background: Most studies found that apolipoprotein B (apo B)-100 is a superior marker for coronary risk to non-high-density lipoprotein (HDL) cholesterol (C). Usually, studies use multivariant analysis with single-point odds/risk ratios. In multivariant analysis, when variables are highly correlated they are difficult to interpret.
View Article and Find Full Text PDFInterference of Plasticizers on Plasma Protein Binding Measurements.
AAPS J
December 2024
Pfizer Worldwide Research and Development, Groton, CT, USA.
Accurate measurement of plasma protein binding (PPB) is of critical importance in drug discovery. Methodologies for PPB measurement continue to evolve to address the challenges of highly bound compounds. In order to generate high quality PPB data, it is crucial to not only apply state-of-the-art methods and highly sensitive and selective detectors, but also use high-quality plasma.
View Article and Find Full Text PDFExploring the link between dietary thiamine and type 2 diabetes mellitus risk in US adults aged 45 years and older: Insights from a cross-sectional investigation.
PLoS One
December 2024
Department of Pharmacy, West China Hospital, Sichuan University, Chengdu, Sichuan, China.
The correlation between dietary thiamine intake and the incidence of type 2 diabetes mellitus (T2DM) remains a subject of controversy within the academic community. While numerous studies have attempted to elucidate this relationship, conclusive evidence remains elusive. A survey of U.
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