AI Article Synopsis
- Verbena officinalis is a traditional Chinese medicine known for treating rheumatism and bronchitis, and recent research identified four new triterpenes (officinalisoids A-D) and 33 known compounds from its aerial parts.
- The chemical structures of the new compounds were analyzed using advanced techniques like NMR and spectroscopy.
- Biological tests showed that one of the compounds (30) has potential anti-inflammatory effects, while another (12) exhibits moderate activity against the dengue virus.
Article Abstract
Verbena officinalis is used as a Chinese folk medicine for the treatment of rheumatism and bronchitis. Herein, four undescribed triterpenes, officinalisoids A-D (1-4), together with thirty-three known compounds (5-37) were isolated from the aerial parts of V. officinalis. The chemical structures of the new compounds were determined by spectrometric data interpretation using NMR, HRESIMS, IR and UV spectroscopy. Biological evaluation results revealed that compound 30 exhibited potential anti-inflammatory activity with IC value of 6.07 μM (CC > 50 μM) and compound 12 showed moderate anti-dengue virus activity with the IC value of 24.55 μM (CC > 50 μM).
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| http://dx.doi.org/10.1016/j.fitote.2023.105670 | DOI Listing |
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