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| http://dx.doi.org/10.1093/icvts/ivad004 | DOI Listing |
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The acute management of penetrating carotid artery injuries-A systematic review.
Ann Vasc Surg
January 2025
Department of Surgery, Division of Vascular Surgery and Endovascular Therapy, Keck School of Medicine of USC, University of Southern California, Los Angeles, CA, USA.
Background: Penetrating carotid artery injuries (CAI) are rare with high morbidity and mortality. We aimed to perform a systematic review of the published literature to evaluate the workup and management of penetrating CAI.
Methods: Studies of acute management of adult trauma patients with penetrating common or internal carotid artery injuries on MEDLINE or EMBASE from 1946 through July 2024 were included following the Preferred Reporting Items for Systematic reviews and Meta-Analyses (PRISMA) statement methodology.
Prolonged grief disorder symptoms and posttraumatic growth among Chinese shidu parents: A latent transition analysis.
Psychol Trauma
January 2025
Department of Experimental Psychology, University of Oxford.
Objective: Chinese shidu parents (bereaved parents who have lost the only child) may experience prolonged grief disorder, as well as posttraumatic growth (PTG). This study aimed to examine their latent classes and transition patterns of prolonged grief disorder symptoms and PTG.
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Humanized dual-targeting antibody-drug conjugates specific to MET and RON receptors as a pharmaceutical strategy for the treatment of cancers exhibiting phenotypic heterogeneity.
Acta Pharmacol Sin
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State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, National Clinical Research Center for Infectious diseases, First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, 310003, China.
Cancer heterogeneity, characterized by diverse populations of tumorigenic cells, involves the occurrence of differential phenotypes with variable expressions of receptor tyrosine kinases. Aberrant expressions of mesenchymal-epithelial transition (MET) and recepteur d'origine nantais (RON) receptors contribute to the phenotypic heterogeneity of cancer cells, which poses a major therapeutic challenge. This study aims to develop a dual-targeting antibody-drug conjugate (ADC) that can act against both MET and RON for treating cancers with high phenotypic heterogeneity.
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Urban Stud
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Newcastle University, UK.
The touristification of Old Havana is resulting in unique patterns of gentrification that rely on a new spatial imaginary, the enforcement of which is resulting in the loss of places for residents to be young. The Cuban state's preservation of significant proportions of social housing as part of its investments in the heritage tourism industry is disrupting common housing-led displacement in the city. The neighbourhood's economic transition is concentrated instead in public spaces, as squares and streets are taken over by new tourist-serving businesses.
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Ren Fail
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Department of Nephrology, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou, China.
Objectives: Vascular access thrombosis (VAT) is a common complication in patients with end-stage renal disease (ESRD), significantly impacting hemodialysis efficacy and patient survival. Currently, temporary dialysis access is typically established deep vein catheterization (VC), however, this method is highly invasive and associated with risks of infection and other complications. This study aims to explore the feasibility of using direct anastomosis indwelling needle puncture (DAINP) for temporary dialysis access.
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