AI Article Synopsis
- The study explores a one-step multi-enzymatic system for producing gluconic acid from starch using whole cells of Aspergillus niger, addressing the high costs of traditional fermentation methods.
- Production achieved impressive results of 134.5 g/L gluconic acid, with a 98.2% yield and a biocatalyst yield of 44.8 g/g over 96 hours.
- This innovative method shows potential for utilizing various substrates that can be converted to glucose, making it a versatile approach in green chemistry.
Article Abstract
The use of multi-enzymatic systems for the industrial production of chemical compounds is currently considered an important green tool in synthetic organic chemistry. Gluconic acid is a multi-functional organic acid widely used in the chemical, pharmaceutical, food, textile, and construction industries. Its industrial production from glucose by fermentation using Aspergillus niger has drawbacks including high costs related to cell growth and maintenance of cell viability. This study presents an innovative one-step multi-enzymatic system for gluconic acid production from starch using Aspergillus niger whole-cells in association with amylolytic enzymes. Using soluble starch as substrate, the following results were achieved for 96 h of reaction: 134.5 ± 4.3 g/L gluconic acid concentration, 98.2 ± 1.3 % gluconic acid yield, and 44.8 ± 1.4 g/g biocatalyst yield. Although the process has been developed using starch as raw material, the approach is feasible for any substrate or residue that can be hydrolyzed to glucose.
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| http://dx.doi.org/10.1016/j.enzmictec.2023.110309 | DOI Listing |
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