Endometriosis affects approximately 10% of premenopausal women worldwide. Despite its impact on quality of life, the delay in diagnosing this chronic disease is well known. Many patients with endometriosis report having suffered from dysmenorrhea and chronic pelvic pain in adolescence or at a young age. However, this painful symptom is often highly underestimated and considered a normal and transient symptom in young women. The real prevalence of endometriosis in adolescence remains uncertain. Some authors recently described at least one ultrasound feature of endometriosis in 13.3% of a general population of adolescent girls, which increased to 35.3% in young girls with severe dysmenorrhea. Dysmenorrhea is classified as primary dysmenorrhea or secondary dysmenorrhea. Primary dysmenorrhea is defined as a menstrual pain without organic disease, while secondary dysmenorrhea is defined as a menstrual pain associated with organic pelvic pathology. Since endometriosis represents the main cause of secondary dysmenorrhea in adolescents and young women, it is important to determine whether the patient has primary dysmenorrhea or additional suggestive symptoms related to endometriosis. Endometriosis in adolescent patients is a challenging problem with clinical and pathological differences compared with its presentation in premenopausal women. Adolescents and young women with dysmenorrhea and painful symptoms that suggest endometriosis should be referred to dedicated endometriosis centers for an early diagnosis and appropriate medical and surgical management. This paper aims to describe the role of dysmenorrhea in adolescents and the management of these young patients to confirm or exclude endometriosis.
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http://dx.doi.org/10.3390/jcm12175624 | DOI Listing |
JMIR Form Res
January 2025
Lyv Healthcare, 6 rue Edouard Nignon, Nantes, FR.
Background: After suffering for an average of 7 years before diagnosis, endometriosis patients are usually left with more questions than answers about managing their symptoms in the absence of a cure. To help women with endometriosis after their diagnosis, we developed an online support program combining user research, evidence-based medicine, and clinical expertise. Structured around CBT and the quality-of-life metrics from the EHP score, the program is designed to guide participants over a 3-month and is available in France.
View Article and Find Full Text PDFBMJ Case Rep
January 2025
Obstetrics and Gynaecology, South Tees Hospitals NHS Foundation Trust, Middlesbrough, UK
Two patients of early adolescence age presented with medically resistant primary dysmenorrhoea. Imaging (MRI scan) confirmed an asymmetric uterine septum with a unilaterally obstructed horn with haematometra. Laparotomy and Tompkins metroplasty was performed to unify the uterine cavity in each case, a technique not used for this condition before.
View Article and Find Full Text PDFBMC Cancer
January 2025
Department of Obstetrics and Gynecology, University Medicine Greifswald, Sauerbruchstr., Greifswald, 17475, Germany.
Background: The diagnosis of rare uterine leiomyosarcoma (uLMS) remains a challenge given the high incidence rates of benign uterine tumors such as leiomyoma (LM). In the last decade, several clinical scores and blood serum markers have been proposed. The aim of this study is to validate and update the pLMS clinical scoring system, evaluating the accuracy of the scoring system by Zhang et al.
View Article and Find Full Text PDFMolecules
December 2024
Graduate School of Pharmaceutical Sciences, College of Pharmacy, Ewha Womans University, Seoul 03760, Republic of Korea.
Leveille is a traditional medicine used to treat migraine headache and dysmenorrhea. In this study, three polyacetylenes, methyl (10,9,16)-16-acetoxy-9-hydroxyoctadeca-10,17-dien-12,14-diynoate (), methyl (10,9,16)-9,16-dihydroxyoctadeca-10-en-12,14-diynoate (), and methyl (10,9,16)-9,16-dihydroxyoctadeca-10,17-dien-12,14-diynoate (), were isolated from the aerial parts of . , together with seven known compounds (-).
View Article and Find Full Text PDFMedicina (Kaunas)
December 2024
Institute of SMART Rehabilitation, Sahmyook University, 815, Hwarang-ro, Seoul 01795, Republic of Korea.
: Autonomic nervous system (ANS) disorders are responsible for primary dysmenorrhea and are closely linked to the spine. This study aims to evaluate the effects of sacroiliac joint manipulation on the ANS and lower abdominal pain in women with primary dysmenorrhea and proposes an alternative treatment method. : A total of 40 participants were randomly assigned; however, 35 participants remained in the final analysis after 5 dropped out; they were assigned to either the sacroiliac joint manipulation group ( = 18) or the superficial heat therapy group ( = 17).
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