AI Article Synopsis
- * The review discusses protective and risk factors associated with asthma, examines current treatment options, and explores the body's immune response, including changes to the epithelial barrier.
- * Additionally, it addresses the genetic and epigenetic influences on asthma and virus susceptibility, as well as the relationship between childhood respiratory infections and the onset of asthma.*
Article Abstract
Several studies have reported that viral infection is closely associated with the onset, progression, and exacerbation of asthma. The purpose of this review is to summarize the role that viral infections have in the pathogenesis of asthma onset and exacerbations, as well as discuss interrelated protective and risk factors of asthma and current treatment options. Furthermore, we present current knowledge of the innate immunological pathways driving host defense, including changes in the epithelial barrier. In addition, we highlight the importance of the genetics and epigenetics of asthma and virus susceptibility. Moreover, the involvement of virus etiology from bronchiolitis and childhood wheezing to asthma is described. The characterization and mechanisms of action of the respiratory viruses most frequently related to asthma are mentioned.
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Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10488270 | PMC |
| http://dx.doi.org/10.3390/jcm12175501 | DOI Listing |
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