Domestic cats are euthanized at high rates in shelters, and appropriate matching between cats and adopters is believed to improve adoption success and reduce euthanasia rates. The ASPCA's Meet Your Match Feline-ality™ program, designed to match cats with owners based on personality and lifestyle, has been implemented in various shelters. This study is the first systematic evaluation of its implementation process and efficacy. Using a controlled interrupted time series design (CITS), the outcome evaluation examined and compared records for five years (2015-2019) from the Seattle Animal Shelter (SAS) and the Multnomah County Animal Shelter located in Portland, Oregon (USA). The outcome evaluation demonstrated no changes in any outcomes (e.g., cat adoptions, euthanasias, returns, transfers, or length of stay) that could be reliably attributed to Feline-ality™. The process evaluation at SAS identified and quantified eight possible errors in implementation that could affect the success of Feline-ality™; the results indicated a 1.6% overall success rate. Whereas the lack of substantive effect may indicate that MYM Feline-ality™ does not perform as purported, it is equally as likely (if not more so) that this absence of evidence of any results reasonably attributable to Feline-ality™ has occurred because the error rate in implementation of the program was very high. The fact that a poorly implemented program necessarily impacts the results of an outcome evaluation underscores the need for process evaluation concurrent with implementation.
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http://dx.doi.org/10.3390/ani13172752 | DOI Listing |
J Infect Dis
January 2025
Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Nobels väg 12A, SE-17177 Stockholm, Sweden.
Background: Sweden introduced HPV vaccination in 2006, administered through opportunistic, subsidized, catch-up and school-based programs. Notably, genital warts (GW) are the first observable clinical outcome following infection by HPV-6/11, targeted by vaccination. We aim to gain knowledge of the incidence of GW in Sweden and evaluate its change throughout vaccination programs.
View Article and Find Full Text PDFClin Infect Dis
January 2025
GSK, Wavre, Belgium.
Background: In this phase 3 trial of an investigational maternal respiratory syncytial virus prefusion F protein-based vaccine (RSVPreF3-Mat), a higher rate of preterm birth was observed in the vaccine (6.8%) versus the placebo group (4.9%).
View Article and Find Full Text PDFJMIR Res Protoc
January 2025
Centre of Excellence in Women and Child Health, Aga Khan University, Karachi, Pakistan.
Background: The neonatal mortality rate in Pakistan is the third highest in Asia, with 8.6 million preterm babies. These newborns require warmth, nutrition, and infection protection, typically provided by incubators.
View Article and Find Full Text PDFJ Med Internet Res
January 2025
Cancer Screening, American Cancer Society, Atlanta, GA, United States.
Background: The online nature of decision aids (DAs) and related e-tools supporting women's decision-making regarding breast cancer screening (BCS) through mammography may facilitate broader access, making them a valuable addition to BCS programs.
Objective: This systematic review and meta-analysis aims to evaluate the scientific evidence on the impacts of these e-tools and to provide a comprehensive assessment of the factors associated with their increased utility and efficacy.
Methods: We followed the 2020 PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) guidelines and conducted a search of MEDLINE, PsycINFO, Embase, CINAHL, and Web of Science databases from August 2010 to April 2023.
Database (Oxford)
January 2025
Department of In Vitro Toxicology and Dermato-Cosmetology (IVTD), Vrije Universiteit Brussel, Laarbeeklaan 103, Brussels 1090, Belgium.
The European Union's ban on animal testing for cosmetic products and their ingredients, combined with the lack of validated animal-free methods, poses challenges in evaluating their potential repeated-dose organ toxicity. To address this, innovative strategies like Next-Generation Risk Assessment (NGRA) are being explored, integrating historical animal data with new mechanistic insights from non-animal New Approach Methodologies (NAMs). This paper introduces the TOXIN knowledge graph (TOXIN KG), a tool designed to retrieve toxicological information on cosmetic ingredients, with a focus on liver-related data.
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