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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10630130 | PMC |
| http://dx.doi.org/10.1038/s41430-023-01341-4 | DOI Listing |
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Clinical Manifestations.
Alzheimers Dement
December 2024
University of Kentucky, Lexington, KY, USA.
Background: Disruption of sleep and circadian rhythms are associated with cognitive decline, preclinical Alzheimer's Disease (AD) pathology, and increased risk of dementia. Alleviating circadian rhythm and sleep disruption may improve cognition and reduce the progression of AD and related dementias (ADRD). Time-restricted eating (TRE), a circadian behavioral intervention that corrects disrupted eating rhythms by aligning food intake to the daytime, has demonstrated improvements in metabolic dysfunction and sleep quality.
View Article and Find Full Text PDFSemantic interference across word classes during lexical selection in Dutch.
Cognition
January 2025
Max Planck Institute for Psycholinguistics, Nijmegen, the Netherlands; Donders Institute for Brain, Cognition and Behaviour, Radboud University, Nijmegen, the Netherlands.
When producing a sentence, speakers must rapidly select appropriate words in the correct order. Models of lexical access often assume that this lexical selection process is competitive and that each word is chosen from a set of competing candidates. Therefore, an important theoretical issue is which factors constrain this choice.
View Article and Find Full Text PDFMisalignment of Circadian Rhythms in Diet-Induced Obesity.
Adv Exp Med Biol
September 2024
Faculty of Medicine, Department of General Surgery, Gazi University, Besevler, Ankara, Turkey.
The biological clocks of the circadian timing system coordinate cellular and physiological processes and synchronize them with daily cycles. While the central clock in the suprachiasmatic nucleus (SCN) is mainly synchronized by the light/dark cycles, the peripheral clocks react to other stimuli, including the feeding/fasting state, nutrients, sleep-wake cycles, and physical activity. During the disruption of circadian rhythms due to genetic mutations or social and occupational obligations, incorrect arrangement between the internal clock system and environmental rhythms leads to the development of obesity.
View Article and Find Full Text PDFA high-light therapy restores the circadian clock and corrects the pathological syndrome generated in restricted-fed mice.
Proc Natl Acad Sci U S A
August 2024
Department of Functional Genomics and Cancer, Institut de Génétique et de Biologie Moléculaire et Cellulaire, Université de Strasbourg, CNRS UMR 7104, Inserm UMR-S 1258, Illkirch F-67400, France.
Article Synopsis
- Time-restricted feeding changes how our genes work in important body parts, but if our body clocks get out of sync, it can lead to health problems like metabolic syndrome.
- Researchers found that using different types of bright light can help fix this misalignment between the body's main clock and other body clocks.
- This bright light therapy could help people who work night shifts or have jet lag to get their body clocks back on track and avoid health issues.
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