Case: A 75-year-old woman presented with left thigh pain 14 years after initial diagnosis of bilateral atypical femoral fractures secondary to chronic bisphosphonate use. New radiographic imaging and magnetic resonance imaging demonstrated bilateral incomplete femur fractures with surrounding marrow edema, cortical remodeling, and periosteal edema in a manner similar to that found 14 years earlier upon original diagnosis.
Conclusion: Recurrence of pain 14 years after initial diagnosis supports consideration of initial surgical management of atypical femur fractures (AFFs), even in patients with nonoperative symptom improvement. Patients who decline surgical intervention should be informed that incomplete AFFs may become a chronic medical condition moving forward.
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http://dx.doi.org/10.2106/JBJS.CC.23.00308 | DOI Listing |
Scand J Med Sci Sports
January 2025
Department of Physical Education and Sports, Faculty of Sport Sciences, University of Granada, Melilla, Spain.
We aimed to determine the persisting effects of various exercise modalities and intensities on functional capacity after periods of training cessation in older adults. A comprehensive search was conducted across the Cochrane Library, PubMed/MEDLINE, Scopus, and Web of Science Core Collection up to March 2024 for randomized controlled trials examining residual effects of physical exercise on functional capacity in older adults ≥ 60 years. The analysis encompassed 15 studies and 21 intervention arms, involving 787 participants.
View Article and Find Full Text PDFActa Paediatr
January 2025
Centre for Adolescent Health, Murdoch Children's Research Institute and Royal Children's Hospital, Parkville, Victoria, Australia.
Aim: Most studies of prepubertal weight and puberty have not used continuous or long follow-up periods. We explored the effect that birth weight and growth trajectories from 0-9 years of age had on starting puberty.
Methods: Data were obtained from 1510 children in Tianjin, China, who were born in 2013 and selected by cluster random sampling.
Singapore Med J
January 2025
Department of Orthopaedic Surgery, National University Health System, Singapore.
Introduction: Increasing age is associated with an increased incidence of necrotising fasciitis. In this study, we aimed to compare the clinical presentation, investigations, microbiology and clinical outcome in elderly (age ≥60 years) and nonelderly (age <60 years) patients with extremity necrotising fasciitis.
Methods: A retrospective review of patients with extremity necrotising fasciitis who were surgically treated between January 2005 and December 2021 was conducted.
Laryngoscope
January 2025
Department of Otolaryngology-Head and Neck Surgery, University of California Irvine, Orange, California, U.S.A.
Background: Posterior nasal nerve (PNN) cryoablation improves chronic rhinitis (CR) symptoms in 70-80% of cases, including clear thin rhinorrhea (CTR). This study's purpose was to determine time to and degree of CTR recurrence following cryoablation.
Methods: A multicenter retrospective cohort study was conducted on patients who underwent PNN cryoablation to treat CR-related CTR refractory to ipratropium bromide nasal spray (IBNS).
Cureus
January 2025
Department of Surgery, King Saud University, College of Medicine, Riyadh, SAU.
Laparoscopic liver resection (LLR) is a minimally invasive surgical approach. Initially utilized for low-risk procedures, such as the resection of benign lesions, now LLR has evolved to include more complex operations such as metastatic lesions. We present in this article two cases with liver metastasis who underwent a successful two-stage total LLR: a 57-year-old man diagnosed with sigmoid cancer and liver metastasis and a 36-year-old man diagnosed with pancreatic neuroendocrine tumor and liver metastasis.
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