Introduction: Pott's disease continues to be rife primarily in ivorian's setting. This large-scale study presents the Ivorian experience in the management of this disease.
Aim: To determine the epidemiological, clinical, paraclinical, therapeutic and evolutionary profile of Pott's disease in Abidjan and to identify the factors associated with neurological compressions.
Methods: Retrospective and analytical study of 420 files of patients suffering from presumptive or confirmed Pott's disease, hospitalized in the rheumatology department of Cocody University Hospital from January 2010 to December 2019.
Results: The hospital frequency of tuberculous spondylodiscitis was 10.2%. Our study population consisted of 223 men and 197 women with an average age of 43.8 ± 15.5 years. A tuberculosis history and a notion of tuberculosis contagion were noted in 4.3% and 13.8% of cases respectively. The mean diagnostic time was 9.67 ± 10.11 months. The main clinical data were spinal syndrome (98.80%) and also tuberculous impregnation signs (84.76%). Neurological complications were noted in 11.66% of cases. Bacilloscopy and PCR BK were positive in 33.71% and 57.14% of cases respectively. Computed tomography was the most requested and performed diagnostic imaging (92.86%). The associated tuberculous targets (11.2%) were visceral (78.70%), in particular pulmonary (75.67%). The mean duration of anti-tuberculosis treatment was 12.42 months with a cure of 97.14% of patients. Diagnostic delay (P = 0.01), gibbosity (P = 0.009), and presence of soft tissue abscesses (P = 0.004) were significantly associated with neurological compressions.
Conclusion: Pott's disease is common in Abidjan and affects young adults. It manifests as a spinal syndrome with tuberculous impregnation signs. Computed tomography was the most performed diagnostic imaging. The factors associated with neurological compressions are: diagnostic delay, gibbosity and soft tissue abscesses.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11099931 | PMC |
Publication Analysis
Top Keywords
Similar Publications
Differences analysis between spinal tuberculosis and brucella spondylitis with preoperative non-invasive differential diagnosis.
Eur Spine J
January 2025
Department of Orthopaedics, Lanzhou University Second Hospital, Lanzhou, Gansu, 730000, China.
Objective: Spinal tuberculosis (STB) and Brucella spondylitis (BS) represent two types of granulomatous infections affecting the spine, which exhibit significant similarities that often result in misdiagnosis and overlooked diagnoses during preoperative evaluations. This study aims to identify non-invasive evaluative indicators that facilitate the differentiation between STB and BS.
Methods: This study conducted a retrospective collection of clinical features, laboratory tests, and imaging characteristics from 89 patients diagnosed with STB and 66 patients diagnosed with BS.
Comparison of the Effects of H37Rv and Infiltration on Tumor Necrosis Factor-Alpha and Interleukin-1 Beta Expression in Osteoblasts.
Surg Infect (Larchmt)
January 2025
First Clinical Medical College, Ningxia Medical University, Yinchuan, China.
This study aims to compare the expression levels of tumor necrosis factor-alpha (TNF-α) and interleukin-1 beta (IL-1β) in osteoblasts infiltrated with H37Rv (H37Rv) and to understand the differential bone destruction in spinal tuberculosis (STB) versus spondylitis (BS). Primary osteoblasts were isolated and cultured from the cranial bones of 2-5 days old mice and characterized by alkaline phosphatase (ALP) staining and alizarin red staining (ARS). H37Rv and were cultured to the logarithmic phase, and transfection solutions were prepared.
View Article and Find Full Text PDFMass-like presentation of primary angiitis of the central nervous system: A clinical note.
Curr J Neurol
April 2024
Brain and Spinal Cord Injury Research Center, Neuroscience Institute, Tehran University of Medical Sciences, Tehran, Iran.
A Lumbar Drug-Resistant Tuberculosis: A Case Report and Review of Literature.
Infect Drug Resist
December 2024
Department of Spine Surgery and Orthopaedics, Xiangya Hospital, Central South University, Changsha, 410008, People's Republic of China.
Introduction: Tuberculosis is prevalent in high-burden countries. However, spinal multi-drug resistant tuberculosis (MDR-TB) in patients with normal immune function is a disease that is prone to misdiagnosis and even delayed diagnosis. Recently, we successfully treated one such patient.
View Article and Find Full Text PDFEfficacy evaluation of a minimally invasive surgical procedure (oblique lateral interbody fusion) for lumbar spinal tuberculosis-retrospective cohort study.
Front Bioeng Biotechnol
December 2024
Department of Orthopaedics, The First Affiliated Hospital of Anhui Medical University, Hefei, Anhui, China.
Objective: In the current study, to demonstrate the advantages of oblique lateral interbody fusion (OLIF), we focused on the therapeutics for lumbar spinal tuberculosis with the comparison of three treatments, including anterior approach, posterior approach, and OLIF combined with posterior percutaneous pedicle screw fixation.
Methods: This study included patients with lumbar spinal tuberculosis from July 2015 to June 2018. We divided these patients into three groups: 35 patients underwent an anterior-only approach (Group A), 36 patients underwent a posterior-only approach (Group B), and 31 patients underwent OLIF combined with posterior percutaneous pedicle screw fixation (Group C).
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!