Kratom availability in California vape shops.

Prev Med Rep

Stanford University School of Medicine, Stanford Prevention Research Center, 3180 Porter Drive, Palo Alto, CA, USA.

Published: October 2023

Kratom products are derived from trees native to Southeast Asia and have dose-dependent stimulant and opioid-like effects. Despite being on the Drug Enforcement Administration "Drugs and Chemicals of Concern List," kratom is legal for sale in most US states. However, there are scarce data on its availability. The goal of this study was to examine kratom availability in vape shops across the state of California and assess shop compliance with a local kratom sales ban (enacted in 2016) in San Diego City. As part of a larger study about retail tobacco marketing near colleges, availability of kratom was assessed in summer 2019 in a random sample of 614 vape shops that was stratified to compare stores near ( 3 miles) and distant (>3 miles) from colleges. Logistic regression examined kratom availability as a function of store type (stores that sold vape products only vs. stores selling other tobacco), nearness to college, and tract-level demographics. Kratom was available in 62.4% of observed stores and more often in vape-and-smoke (81.1%) than vape-only shops (11.5%, AOR = 40.4, 95% CI = 23.3-74.1). Kratom availability did not differ by nearness to colleges. In San Diego City, 46.2% of observed stores (95% CI = 28.8-64.5) sold kratom products. Findings indicate that kratom was available in the majority of vape shops and most commonly in vape-and-smoke shops. Widespread availability in tobacco specialty shops suggests the need for research on dual use with tobacco, kratom advertising and cross-product promotion, and the potential of state and local tobacco retail licensing to prohibit sales.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10481347PMC
http://dx.doi.org/10.1016/j.pmedr.2023.102380DOI Listing

Publication Analysis

Top Keywords

kratom availability
16
vape shops
16
kratom
12
kratom products
8
san diego
8
diego city
8
observed stores
8
shops
7
availability
6
vape
5

Similar Publications

Postmortem distribution of mitragynine and 7-hydroxymitragynine in 51 cases.

J Anal Toxicol

December 2024

Tarrant County Medical Examiner's Office, Fort Worth, TX 76104, United States.

The prevalence of mitragynine (kratom) in forensic toxicology casework has steadily increased over time. Readily available and currently legal, mitragynine is widely used for its stimulant and, depending on concentration, sedative effects. Our laboratory analyzed various fluid and tissue specimens from 51 postmortem cases to investigate the distribution of mitragynine and its active metabolite 7-hydroxymitragynine.

View Article and Find Full Text PDF

Quantification of 11 kratom alkaloids including mitragynine and its main metabolites in human plasma using LC-MS/MS.

Anal Bioanal Chem

December 2024

iC42 Clinical Research and Development, Department of Anesthesiology, Anschutz Medical Campus, University of Colorado, 12705 E Montview Blvd, Suite 200, Aurora, CO, 80045, USA.

Recently in the USA, kratom consumers increasingly report use of the plant for self-treatment of mood ailments, the lack of energy, chronic pain, and opioid withdrawal and dependence. Several alkaloids are present in kratom leaves, but limited data are available on their pharmacokinetics/pharmacodynamics, except for mitragynine. To support clinical studies, a high-performance liquid chromatography-tandem mass spectrometry assay for the simultaneous quantification of 11 kratom alkaloids in human plasma was developed and validated.

View Article and Find Full Text PDF

Kratom Alkaloids for the Treatment of Alcohol Use Disorder.

ACS Chem Neurosci

December 2024

Department of Pharmacological & Pharmaceutical Sciences, College of Pharmacy, University of Houston, Houston, Texas 77204, United States.

Article Synopsis
  • Alcohol use disorder (AUD) leads to significant mortality and economic costs, with limited FDA/EMA-approved treatments available, many of which have adverse effects.
  • Kratom alkaloids show promise in reducing alcohol intake and withdrawal symptoms in animal studies by acting on specific opioid receptors.
  • The article reviews recent preclinical studies on kratom for AUD treatment, discusses approved and repurposed drugs, and outlines caveats and future research needs.
View Article and Find Full Text PDF

Obesity is a global health concern, steadily rising and posing risks to various health conditions. Despite available antiobesity drugs, their withdrawal due to severe side effects highlights the need for safer alternatives. Natural products, particularly mixed herbal formulations, present a promising avenue in obesity research.

View Article and Find Full Text PDF

In vitro antifungal activities of medicinal plants used for treatment of candidiasis in Pader district, Northern Uganda.

Trop Med Health

November 2024

Department of Plant Science, Microbiology and Biotechnology, School of Biosciences, College of Natural Sciences, Makerere University, P. O. Box 7062, Kampala, Uganda.

Background: The emergence of multidrug resistant Candida species to available drugs has led to renewed interest in the use of herbal medicines globally. This study scientifically verified antifungal effectiveness of five commonly used plant species in Pader district, against selected pathogenic candida strains.

Methods: Powdered roots of Momordica foetida, Sansevieria dawei and Distimake dissectus; and stem barks of Khaya anthotheca and Mitragyna rubrostipulata were extracted sequentially using petroleum ether and methanol, respectively; and total water extraction at 24.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!