Platinum(II)-based metallacycles/cages have obtained tremendous attention due to their fascinating topology and wide range of applications, such as fluorescent materials, cell imaging, and tumor treatment. In this work, a metallatetragon () was constructed from 4-(4-(1,2,2-triphenylvinyl)phenyl)pyridine () and 90° -Pt(II) () in acetone through the strategy called "coordination driven self-assembly". Interestingly, through co-assembly of and poly(ethylene glycol)-modified tetraphenylethylene (), fluorescent nanotheranostics, which could generate singlet oxygen (O) under the NIR irradiation and release Pt drugs under a low-pH microenvironment, were prepared successfully. The obtained theranostics could realize living cell imaging and synergistic chemo-photodynamic therapy and .
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