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http://dx.doi.org/10.1038/d41586-023-02739-7 | DOI Listing |
Am J Physiol Heart Circ Physiol
January 2025
Neurovascular Research Laboratory, School of Kinesiology, Western University, London, Ontario, Canada.
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View Article and Find Full Text PDFEur J Appl Physiol
January 2025
Department of Kinesiology and Health Promotion, University of Kentucky, 1210 University Drive, Lexington, KY, 40526, USA.
Purpose: The purpose of this study was to examine the sex-specific influence of expected exercise duration on the physiological responses to RPE-clamp exercise anchored to RPE 15 with participants being deceived into believing the RPE-clamp exercise would last for 20-, 30-, or 40-min, but all trials were 30-min.
Methods: Twelve males and 12 females completed a graded exercise test followed by randomly ordered RPE-clamp trials at RPE15 on the Borg 6-20 scale where subjects were deceived into expecting exercise to last for either 20-, 30-, or 40-min, but the actual duration for each trial was 30-min. Separate 2 (Sex [Male vs.
Diabetes Res Clin Pract
January 2025
Department of Endocrinology-Diabetology-Nutrition, Jean Verdier Hospital, APHP, CINFO, Bondy, France. Electronic address:
Although often overlooked sleep apnea has emerged as a significant public health concern. Obstructive sleep apnea (OSA) and diabetes commonly co-exist with a vicious cycle worsening the incidence and severity of both conditions. OSA has many implications including cardiometabolic disorders and impaired cardiovascular (CV) prognosis.
View Article and Find Full Text PDFAndes Pediatr
August 2024
Departamento de Ciencias de la Actividad Física, Universidad Católica del Maule, Talca, Chile.
Unlabelled: Cardiorespiratory fitness can be assessed by direct, indirect, maximal, and moderate effort, running, cycling, or walking methods.
Objective: To predict maximum oxygen consumption (V O2max) from the six-minute walk test in schoolchildren.
Patients And Method: 459 students were included, 215 were male and 244 were female, aged 11.
Turk J Biol
October 2024
Department of Genetics and Bioengineering, Faculty of Engineering, Yeditepe University, İstanbul, Turkiye.
MEIS1, a member of the TALE-type homeobox gene family, has emerged as a pivotal regulator of cardiomyocyte cell cycle arrest and represents a promising therapeutic target. Our study reveals that inhibition of MEIS1 using two novel small molecules, MEISi-1 and MEISi-2, significantly enhances neonatal cardiomyocyte proliferation and cytokinesis. Specifically, MEISi-1 and MEISi-2 increased the proportion of proliferating cardiomyocytes (Ph3+TnnT cells) up to 4.
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