Customized photorefractive keratectomy with minimal tissue ablation combined with corneal cross-linking seems to be a long-term safe and effective strategy for anatomical and visual management of keratoconus, postsurgical ectasia, and other ectasia management. Multiple published studies, many with long-term follow-up, have supported the Athens Protocol and its various forms as a means to manage corneal ectatic disorders, which not only stabilize corneal shapes but also improve functional vision.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10476591PMC
http://dx.doi.org/10.1097/ICO.0000000000003320DOI Listing

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