AI Article Synopsis
- Granulosa cells are essential for producing estrogens that support follicular growth in buffalo.
- The study investigated how testosterone affects estrogen production in these cells.
- Findings revealed that adding testosterone at a specific concentration boosted estrogen synthesis in granulosa cells, contributing to understanding of ovarian hormone regulation.
Article Abstract
Granulosa cells (GCs) synthesize estrogens needed for follicular growth. However, the effects of androgen on estrogen production in buffalo GCs remain unclear. In this study, the impacts of testosterone on estrogen synthesis in buffalo GCs were examined. The results showed that testosterone that was added to cell medium at a concentration of 10 mol/L and applied to GCs for 48 or 72 h enhanced the estrogen synthesis of buffalo GCs. This study provides a theoretical basis for further exploration of ovarian endocrine mechanism for steroidogenesis.
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| http://dx.doi.org/10.1111/rda.14467 | DOI Listing |
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