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Doxycycline post-exposure prophylaxis (doxy-PEP) is a preventative strategy demonstrated to reduce bacterial sexually transmitted infections in high-risk populations. However, the impact of doxy-PEP on antibiotic resistance acquisition in key members of our microbiomes, is as of yet unclear. For example, commensal are known reservoirs of resistance for gonococci through horizontal gene transfer (HGT), and are more likely to experience bystander selection due to doxy-PEP as they are universally carried.
View Article and Find Full Text PDFA case of acquired syphilis in an infant through mouth-to-mouth transmission of prechewed food.
Int J STD AIDS
January 2025
Department of Dermatology, The First Hospital of Hebei Medical University, Shijiazhuang, China.
Background: Patients with syphilis are the only source of infection, which can be transmitted through sexual contact and mother-to-child and blood transmission, and rarely through contaminants. The clinical manifestations of syphilis are complex and variable, and can be easily misdiagnosed. This article reports a case of syphilis in a child with "psoriasis"-like lesions who was fed pre-chewed food.
View Article and Find Full Text PDFDisruption of Sex-Linked Causes ZW Female-to-Male Sex Reversal in the Japanese Frog .
Biomolecules
December 2024
Preservation and Research Center, City of Yokohama, Yokohama 241-0804, Japan.
is an ancestral homologous gene of the male-determining in eutherian mammals and determines maleness in medaka fish. In the Japanese frog, , is located on the Z and W chromosomes. To assess the sex-determining function of in this frog, we investigated its expression in gonads during early tadpole development and conducted genome-editing experiments.
View Article and Find Full Text PDFActivity Space Mapping and Pre-Exposure Prophylaxis Uptake Among Gay, Bisexual, and Other Sexual Minority Men in Small Cities and Towns in the United States.
AIDS Behav
January 2025
Department of Social and Behavioral Sciences, Yale School of Public Health, 60 College Street, New Haven, CT, 06510, USA.
In the US, gay, bisexual, and other sexual minoritized men (GBSMM) remain disproportionately impacted by HIV, and continue to experience unmet needs for pre-exposure prophylaxis (PrEP). A growing body of literature has underscored the need to consider the geographic factors of HIV prevention, particularly beyond administrative boundaries and towards localized spaces that influence the accessibility and utilization of health-promoting resources. Therefore, the purpose of this study is to examine the associations of driving times from activity spaces to PrEP offering facilities and individual PrEP uptake.
View Article and Find Full Text PDFInvestigation of Sexual Education Programs for Adolescents With Autism and the Role of Parents in Providing Support.
Mater Sociomed
January 2024
Department of Preschool Education Sciences and Edicational Design, University of the Aegean.
Background: Sexual education of adolescents with autism spectrum disorder (ASD) is a complex challenge, as the lack of specialized programs limits effective learning. Adolescents with ASD have difficulty understanding abstract concepts such as consent, personal boundaries and safety, which increases the risk of exploitation.
Objective: This study seeks to examine the experiences and challenges parents face in providing sexuality education to their children with ASD, highlighting the need for programs that respond to the particular needs of these adolescents.
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