Rapid -weighted MRI using multishot EPI with retrospective motion and phase correction in the emergency department.

Purpose: Brain MRI is increasingly used in the emergency department (ED), where -weighted MRI is an essential tool for detecting hemorrhage and stroke. The goal of this study was to develop a rapid -weighted MRI technique capable of correcting motion-induced artifacts, thereby simultaneously improving scan time and motion robustness for ED applications.

Methods: A 2D gradient-echo (GRE)-based multishot EPI (msEPI) technique was implemented using a navigator echo for estimating motion-induced errors. Bulk rigid head motion and phase errors were retrospectively corrected using an iterative conjugate gradient approach in the reconstruction pipeline. Three volunteers and select patients were imaged at 3 T and/or 1.5 T with an approximately 1-min full-brain protocol using the proposed msEPI technique and compared to an approximately 3-min standard-of-care GRE protocol to examine its performance.

Results: Data from volunteers demonstrated that in-plane motion artifacts could be effectively corrected with the proposed msEPI technique, and through-plane motion artifacts could be mitigated. Patient images were qualitatively reviewed by one radiologist without a formal statistical analysis. These results suggested the proposed technique could correct motion-induced artifacts in the clinical setting. In addition, the conspicuity of susceptibility-related lesions using the proposed msEPI technique was comparable, or improved, compared to GRE.

Conclusion: A 1-min full-brain -weighted MRI technique was developed using msEPI with a navigator echo to correct motion-induced errors. Preliminary clinical results suggest faster scans and improved motion robustness and lesion conspicuity make msEPI a competitive alternative to traditional -weighted MRI techniques for brain studies in the ED.