Herein, a highly efficient, scalable, and cascade [1,5] hydride transfer/cyclization method for constructing unique spirocyclic pyrazolone-pyrrolo[4,3,2-]quinoline structures C(sp)-H functionalization is achieved, using pyrazolones and oxindoles attached to C4 amines. This strategy represents a limited approach utilizing C-H activation to construct spirocyclic pyrazolone scaffolds with moderate to excellent reaction performance.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1039/d3ob01063e | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Assembly of spirocyclic pyrazolone-pyrrolo[4,3,2-]quinoline skeleton cascade [1,5] hydride transfer/cyclization by C(sp)-H functionalization.
Org Biomol Chem
September 2023
State Key Laboratory of Southwestern Chinese Medicine Resources, School of Pharmacy and College of Medical Technology, Chengdu University of Traditional Chinese Medicine, Chengdu 611137, China.
Herein, a highly efficient, scalable, and cascade [1,5] hydride transfer/cyclization method for constructing unique spirocyclic pyrazolone-pyrrolo[4,3,2-]quinoline structures C(sp)-H functionalization is achieved, using pyrazolones and oxindoles attached to C4 amines. This strategy represents a limited approach utilizing C-H activation to construct spirocyclic pyrazolone scaffolds with moderate to excellent reaction performance.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!