AI Article Synopsis
- The rising prevalence of food allergies emphasizes the need for new prevention methods, effective treatments, and reliable risk assessment tools due to the varying degrees of allergen digestion in individuals.
- Recent research highlights the importance of understanding the digestive system and its impact on food allergens, focusing on how food processing and digestion contribute to allergen stability.
- It is noted that allergen digestibility is influenced by food processing, digestive conditions, and the overall food matrix, making it difficult to predict allergen immunogenicity based solely on protein stability.
Article Abstract
Purpose Of Review: The globally rising food allergy prevalence is associated with the urgent need for new disease prevention methods, efficient treatment, and reliable risk assessment methods for characterization of food allergens. Due to inter-individual variations in the digestive system, food allergens are degraded to a different extent in each person. Food processing also influences allergen digestion.
Recent Findings: In this review, we provide an overview of the digestive system with focus on relevance for food allergy. Main food proteins causing allergic reactions are evaluated, and the combined role of food processing and digestion for allergen stability is highlighted. Finally, clinical implications of this knowledge are discussed. Recent literature shows that allergen digestibility is dependent on food processing, digestive conditions, and food matrix. Digestion affects proteins allergenicity. It is currently not possible to predict the immunogenicity of allergens solely based on protein stability.
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|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10506954 | PMC |
| http://dx.doi.org/10.1007/s11882-023-01107-9 | DOI Listing |
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