A Case of Functional Bowel Disease Misdiagnosed as Carcinoid Syndrome.

ACG Case Rep J

Attending Gastroenterologist Gastroenterology Institute of Fort Lauderdale and Division of Gastroenterology, Holy Cross Hospital, Fort Lauderdale, FL.

Published: September 2023

An elevated urinary 5-hydroxyindoleacetic acid (U5-HIAA) is typically thought of to be related to carcinoid syndrome. It is widely known that several other etiologies can cause high levels; however, those etiologies typically cause mild elevations. We present a unique situation of a highly elevated U5-HIAA not because of a neuroendocrine tumor. Gastroenterologists need to have an approach in mind if they encounter this predicament. We aim to raise awareness of this situation to emphasize the importance of a thorough medication history and avoid unnecessary testing.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10470757PMC
http://dx.doi.org/10.14309/crj.0000000000001136DOI Listing

Publication Analysis

Top Keywords

carcinoid syndrome
8
case functional
4
functional bowel
4
bowel disease
4
disease misdiagnosed
4
misdiagnosed carcinoid
4
syndrome elevated
4
elevated urinary
4
urinary 5-hydroxyindoleacetic
4
5-hydroxyindoleacetic acid
4

Similar Publications

Ectopic ACTH syndrome caused by thymic neuroendocrine tumour - stages of treatment.

Endokrynol Pol

December 2024

Department of Endocrinology and Neuroendocrine Tumours, Medical University of Silesia, Katowice, Poland.

Not required for Clinical Vignette.

View Article and Find Full Text PDF

Severe Ectopic Adrenocorticotropic Hormone Syndrome Due to Pulmonary Carcinoid Tumor: A Case Report and Literature Review.

AACE Clin Case Rep

August 2024

Division of Endocrinology, Department of Medicine, Duke University, Durham, North Carolina.

Background/objective: Pulmonary carcinoid tumors are a rare cause of Cushing's syndrome and usually present with an indolent course. Here, we present a case of rapid onset and severe Cushing's syndrome due to a typical pulmonary carcinoid tumor.

Case Report: A 32-year-old woman developed diabetes, hypertension, and weight gain of 50 pounds over 3 months.

View Article and Find Full Text PDF

[An unusual tricuspid regurgitation].

G Ital Cardiol (Rome)

January 2025

U.O. Cardiologia, Dipartimento di Specialità Medico-Chirurgiche, Scienze Radiologiche e Sanità Pubblica, Università degli Studi, Brescia.

Tricuspid regurgitation can be due to different causes and mechanisms. Among these, cardiac involvement in carcinoid disease is a rare cause of tricuspid valve disease with a peculiar echocardiographic aspect. We report the case of a 59-year-old woman, with no past medical history, who was recently found to have a heart murmur and signs of right heart failure.

View Article and Find Full Text PDF

Small intestinal neuroendocrine tumors (SI-NETs) are characterized by carcinoid syndrome and carcinoid heart disease (CHD). The aim of the present study was to identify early risk markers for carcinoid heart disease and survival in a prospective median-term follow-up setting. We measured 5-HIAA and cumulative 5-HIAA exposure (Cum-5-HIAA) based on repeated measurements, proBNP, vascular function, hepatic tumor load, and transthoracic echocardiography (TTE) at baseline and during the median 5-year follow-up.

View Article and Find Full Text PDF

Ectopic adrenocorticotropic hormone (ACTH)-dependent Cushing is a rare syndrome. We present a case that illustrates the diagnostic and therapeutic challenges of ectopic Cushing. A 35-year-old woman presented to the outpatient clinic for evaluation of progressive weight gain, muscle weakness, easy bruising, uncontrolled hypertension, and hyperglycemia.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!