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Multi-Omics Research on Angina Pectoris: A Novel Perspective.
Aging Dis
December 2024
Department of Psycho-cardiology, Beijing Anzhen Hospital, Capital Medical University, Beijing, China.
Angina pectoris (AP), a clinical syndrome characterized by paroxysmal chest pain, is caused by insufficient blood supply to the coronary arteries and sudden temporary myocardial ischemia and hypoxia. Long-term AP typically induces other cardiovascular events, including myocardial infarction and heart failure, posing a serious threat to patient safety. However, AP's complex pathological mechanisms and developmental processes introduce significant challenges in the rapid diagnosis and accurate treatment of its different subtypes, including stable angina pectoris (SAP), unstable angina pectoris (UAP), and variant angina pectoris (VAP).
View Article and Find Full Text PDFVasospastic Angina in Adolescents: A Case Report of a 15-Year-Old Boy.
Cureus
November 2024
Department of Cardiology, Aizawa Hospital, Matsumoto, JPN.
This case report describes a 15-year-old boy who presented with vasospastic angina (VSA). His symptoms included chest and back pain, nausea, and respiratory distress. After undergoing diagnostic tests, including coronary angiography and an acetylcholine provocation test, the patient was diagnosed with VSA.
View Article and Find Full Text PDFRare Clinical Manifestation of Vasculitis.
Diagnostics (Basel)
November 2024
Faculty of Medicine, "Grigore T. Popa" University of Medicine and Pharmacy, 700115 Iași, Romania.
Article Synopsis
- ANCA-associated vasculitis is linked to a significantly higher risk of cardiovascular issues, with rare but serious coronary artery involvement.
- A 68-year-old woman with p-ANCA vasculitis and severe kidney disease presented with chest pain and low blood pressure, showing signs of coronary vasospasm rather than blockage during testing.
- Treatment with medications such as amlodipine and corticosteroids successfully resolved her symptoms, highlighting the immune-mediated nature of the vascular inflammation.
SoutheAsTern eUrope microciRculATION (SATURATION) registry - Design and rationale.
Cardiovasc Revasc Med
December 2024
Institute for Cardiovascular Diseases "Dedinje", Belgrade, Serbia; Faculty of Medicine, University of Belgrade, Belgrade, Serbia. Electronic address:
Background: A considerable number of symptomatic patients leave the cardiac catheterization lab without a definitive diagnosis for their symptoms because no epicardial stenoses are found. The significance of disorders of coronary microvasculature and vasomotion as the cause of symptoms and signs of ischemia has only recently been appreciated. Today we have a wide spectrum of invasive coronary physiology tools but little is known about when and how these tools are used in clinical practice.
View Article and Find Full Text PDFImmunotherapy-mediated myocarditis and concurrent vasospastic angina in a patient with established ischaemic heart disease: a case report.
Eur Heart J Case Rep
December 2024
Department of Cardio-oncology, Victorian Heart Hospital, 631 Blackburn Road, Clayton, Melbourne, VIC 3168, Australia.
Background: Immunotherapy has become a pillar of modern oncological management but is associated with significant immunotherapy-related adverse events (IRAEs). While myocarditis is a prominent IRAE which clinicians are increasingly aware of, immunotherapy-related coronary vasospasm is far less appreciated and can be especially difficult to elucidate in pre-existing coronary artery disease. This case demonstrates the approach to diagnosis and management of multiple cardiovascular and non-cardiovascular IRAEs.
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