Objectives: To investigate the agreement between continuous noninvasive blood pressure measurement with the ClearSight system (cNIBP-CS) and standard intermittent noninvasive blood pressure measurement (iNIBP) in patients with peripheral arterial disease (PAD). Additionally, the influence of vasoactive medication on potential measurement differences was assessed.
Design: A secondary analysis of a randomized controlled trial.
Setting: At a university hospital.
Participants: Thirty-four patients with PAD undergoing percutaneous transluminal angioplasty of the lower limbs.
Interventions: None.
Measurements And Main Results: Continuous noninvasive blood pressures were measured with the "ClearSight" system and compared to standard iNIBPs. Bland-Altman analysis revealed a mean bias of 13 mmHg (±15) between cNIBP-CS and iNIBP, with 95% limits of agreement (LOA) ranging from -17 to 42 mmHg. When comparing both medication groups, a similar mean bias was found for phenylephrine and dobutamine (12 mmHg [±13] and 13 mmHg [±13], respectively).
Conclusion: In this study, in patients with PAD, cNIBP-CS showed an underestimation of blood pressure compared to iNIBP in phenylephrine- and dobutamine-treated patients. Compared to previous studies, a larger bias and wider 95% LOA were found.
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http://dx.doi.org/10.1053/j.jvca.2023.08.004 | DOI Listing |
Biol Trace Elem Res
January 2025
Laboratory for Toxicology and Micronutrient Metabolism, Chemical Pathology Department, College of Medicine, University of Ibadan, Ibadan, Nigeria.
Auto-mechanics who often work without safety measures are vulnerable to the harmful effects of toxic metals like lead (Pb) and cadmium (Cd). These toxic metals exert their deleterious effect by interacting with the micronutrients at their primary site of action. This study aimed to investigate the effects of toxic metal exposure on serum micronutrient levels of auto-mechanics in Nigeria.
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Department of Respiratory and Critical Care Medicine, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, People's Republic of China.
The traditional Chinese medicine compound preparation known as Jinbei Oral Liquid (JBOL) consists of 12 herbs, including Astragalus membranaceus (Fisch.) Bge, Codonopsis pilosula (Franch.) Nannf, et al.
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January 2025
MRC Epidemiology Unit, School of Clinical Medicine, University of Cambridge, Cambridge, UK.
Aims/hypothesis: UK standard care for type 2 diabetes is structured diabetes education, with no effects on HbA, small, short-term effects on weight and low uptake. We evaluated whether remotely delivered tailored diabetes education combined with commercial behavioural weight management is cost-effective compared with current standard care in helping people with type 2 diabetes to lower their blood glucose, lose weight, achieve remission and improve cardiovascular risk factors.
Methods: We conducted a pragmatic, randomised, parallel two-group trial.
Hypertens Res
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Laboratory of Clinical Investigation, National Institute on Aging, National Institutes of Health, Baltimore, 21224, MD, USA.
The brainstem plays a vital role in regulating blood pressure, and disruptions to its neural pathways have been linked to hypertension. However, it remains unclear whether subtle microstructural changes in the brainstem are associated with an individual's blood pressure status. This exploratory, cross-sectional study investigated the relationship between brainstem microstructure, myelination, and hypertensive status in 116 cognitively unimpaired adults (aged 22-94 years).
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January 2025
Department of Pathology, The Second Hospital of Hebei Medical University, Shijiazhuang, Hebei, China.
To investigate the correlation between the density and volume of epicardial adipose tissue(EAT)and acute coronary syndrome (ACS). This study included 355 subjects (mean age: 60.65 ± 9.
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