AI Article Synopsis

  • Diagnosing drug-induced acute pancreatitis is often missed, as it's a rare condition that requires ruling out other common causes like alcohol and gallstones.
  • Levofloxacin, an antibiotic used for bacterial infections, can occasionally lead to acute pancreatitis, despite its more common side effects.
  • A case study highlights a woman who developed acute pancreatitis after taking levofloxacin for a urinary tract infection, with diagnosis confirmed through clinical and laboratory evaluations.

Article Abstract

Diagnosing acute pancreatitis induced by any drug is often overlooked and warrants careful evaluation. Drug-induced acute pancreatitis is relatively rare, and diagnosis of exclusion after ruling out alcohol, gallstones, hypertriglyceridemia, and intervention. Levofloxacin, a class of fluoroquinolones, is generally recommended against various bacterial infections. While levofloxacin is mainly known for its potential side effects, such as photosensitivity and liver toxicity, it can also rarely induce acute pancreatitis. We report a case of acute pancreatitis in a female patient precipitated by levofloxacin. The patient exhibited typical manifestations of acute pancreatitis and had been taking levofloxacin for a urinary tract infection over the past three days. After ruling out other possible causes, her clinical presentation, laboratory results, and imaging findings confirmed levofloxacin-induced acute pancreatitis.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10467605PMC
http://dx.doi.org/10.7759/cureus.42743DOI Listing

Publication Analysis

Top Keywords

acute pancreatitis
28
levofloxacin-induced acute
8
acute
7
pancreatitis
7
rare case
4
case levofloxacin-induced
4
pancreatitis case
4
case report
4
report literature
4
literature review
4

Similar Publications

Acute pancreatitis with panniculitis: a rare and striking clinical presentation.

Rev Esp Enferm Dig

January 2025

Gastroenterology, Unidade de Saúde Local do Algarve-Unidade de Faro, Portugal .

Pancreatic panniculitis is a rare dermatological manifestation of pancreatic disorders, characterized by painful, erythematous nodules. We present the case of an 84-year-old woman with acute pancreatitis who developed erythematous-violaceous nodular lesions on her lower limbs. Histopathological examination revealed lobular panniculitis with fat necrosis and ghost adipocytes, confirming the diagnosis.

View Article and Find Full Text PDF

Objective: This research aimed to analyze the impact of hemorrhagic fever with renal syndrome (HFRS) with acute pancreatitis (AP) on the severity and prognosis of patients, screen the risk factors of HFRS with AP, and establish a nomogram model.

Methods: Data were collected from HFRS patients at the First Affiliated Hospital of Dali University and Dali Prefecture People's Hospital (2013-2023). Patients were divided into HFRS with AP ( = 34) and HFRS without AP groups ( = 356).

View Article and Find Full Text PDF

Aim: To describe the effects of Glucagon-like peptide-1 receptor agonists (GLP-1RA) in patients with familial partial lipodystrophy (FPLD) assessed in a real-life setting in a national reference network.

Patients And Methods: We retrospectively collected clinical and metabolic parameters in patients with FPLD in the French lipodystrophy reference network, who initiated GLP-1RA. Data were recorded before, at one-year (12 ± 6 months) and at the latest follow-up on GLP-1RA therapy (≥18 months).

View Article and Find Full Text PDF

Background: The use of antibiotic therapy in acute pancreatitis remains controversial and is currently recommended only for confirmed infections of peripancreatic necrosis. However, reliable early predictors of septic complications and unfavorable outcomes are substantially lacking.

Methods: Patients with acute pancreatitis were retrospectively reviewed and divided into two groups: one with a septic course defined by pathogen detection [GERM(+)] and one without [GERM(-)].

View Article and Find Full Text PDF

Lineage tracing of pancreatic cells for mechanistic and therapeutic insights.

Trends Endocrinol Metab

January 2025

CAS CEMCS-CUHK Joint Laboratories, New Cornerstone Investigator Institute, State Key Laboratory of Cell Biology, Shanghai Institute of Biochemistry and Cell Biology, Center for Excellence in Molecular Cell Science, Chinese Academy of Sciences, University of Chinese Academy of Sciences, Shanghai, China; School of Life Science and Technology, ShanghaiTech University, Shanghai, China; Key Laboratory of Systems Health Science of Zhejiang Province, School of Life Science, Hangzhou Institute for Advanced Study, University of Chinese Academy of Sciences, Hangzhou, China. Electronic address:

Recent advances in lineage-tracing technologies have significantly improved our understanding of pancreatic cell biology, particularly in elucidating the ontogeny and regenerative capacity of pancreatic cells. A deeper appreciation of the mechanisms underlying pancreatic cell identity and plasticity holds the potential to inform the development of new therapeutic modalities for conditions such as diabetes and pancreatitis. With this goal in mind, here we summarize advances, challenges, and future directions in tracing pancreatic cell origins and fates using lineage-tracing technologies.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!