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Anti-cancer activity of leaves explained using its compounds docked with p53. | LitMetric

Anti-cancer activity of leaves explained using its compounds docked with p53.

Bioinformation

Department of Biochemistry, Rathnavel Subramaniam College of Arts and Science, Bharathiar University, Coimbatore - 641402, India.

Published: October 2022

Extensive research on the mutant P53 protein has identified its pivotal role in anti-apoptosis mechanisms, drug resistance, and cancer progression in OSCC. The mass spectrum revealed the pharmacologically significant bioactive compounds reported for the first time in C cainito. Molecular docking investigation has identified four potential new P53 inhibitors compared with the standard P53 inhibitors. Hence, this analysis reinforces the likelihood of anti-cancer activities in leaves.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10465767PMC
http://dx.doi.org/10.6026/97320630018870DOI Listing

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