Rationale: Iodine-induced hyperthyroidism and triiodothyronine (T3) thyrotoxicosis in patients who routinely gargle with povidone-iodine (PVP-I) gargling solution are rare in Japan.
Patient Concerns: A 50-year-old man presented to our hospital for a close examination of an enlarged thyroid, which was noted during a complete health checkup. The thyroid was slightly enlarged with no palpable nodules. He had an increased appetite but no weight gain. He had been routinely gargling with PVP-I gargling solution 4 times daily for >10 years. He had no history of thyroid disease.
Diagnoses: Test results revealed suppressed thyroid-stimulating hormone, normal free thyroxine, and increased free triiodothyronine levels, leading to the diagnosis of T3 thyrotoxicosis.
Interventions: The patient agreed to stop gargling with PVP-I gargle solution.
Outcomes: The free triiodothyronine and thyroid-stimulating hormone levels returned to normal at 18 and 21 weeks, respectively, after discontinuation of PVP-I gargling. After an improvement in thyroid function, he gained 5 kg in 1 year.
Lessons: To our knowledge, this is the first case report that describes PVP-I gargle-induced T3 thyrotoxicosis in a healthy individual without thyroid disease. In Japan, which is an iodine-sufficient country, considering the possibility of high-dose iodine intake-induced thyrotoxicosis due to long-term PVP-I gargling or other causes is necessary, even in individuals with no history of thyroid disease.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10470704 | PMC |
| http://dx.doi.org/10.1097/MD.0000000000034631 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Influence of three antiseptic mouthwashes on microtensile bond strength of self-etch adhesive to dentin: Rinsing versus non-rinsing with water.
Heliyon
December 2024
Department of Advanced General Dentistry, Faculty of Dentistry, Mahidol University, Bangkok, 10400, Thailand.
Objective: The purpose of this study was to examine the effect of several antiseptic mouthwashes on the dentin microtensile bond strength of self-etch adhesive, considering the influence of rinsing with water.
Methods: Forty flat dentin surfaces were produced by sectioning sound extracted third molars. They were randomly divided into four main groups: (1) artificial saliva (control); (2) 1 % hydrogen peroxide; (3) 0.
SKIN ANTISEPSIS PRACTICES FOR CENTRAL NEURAXIAL BLOCKADE.
J Ayub Med Coll Abbottabad
November 2024
Department of Anaesthesiology, Aga Khan University Hospital, Karachi-Pakistan.
Background: Skin antisepsis is essential before the central neuraxial blockade. Various antiseptic solutions are in clinical use, like povidone-iodine, alcohol, or chlorhexidine. This study was conducted to assess current practices for skin antisepsis before central neuraxial blockade and observe the compliance of anaesthesiologists with international standards in Teaching Hospitals in Karachi, Pakistan.
View Article and Find Full Text PDFAntiviral activity of povidone-iodine gargle and mouthwash solution against Enterovirus A71, Coxsackieviruses A16, A10 and A6.
Trop Biomed
September 2024
Department of Biomedical Science, Faculty of Medicine, Universiti Malaya, Kuala Lumpur, Malaysia.
Hand, Foot and Mouth Disease (HFMD), a highly contagious viral disease common among infants and young children, is primarily caused by Enterovirus A71 (EV-A71) and Coxsackievirus A16 (CVA16). Nonetheless, emerging enteroviruses, such as CV-A10 and CV-A6, have also caused widespread outbreaks globally, in part due to the absence of effective antiviral therapies, and the high personto-person transmission rate. Person-to-person transmission is usually through fecal-oral or oral-oral routes, and sometimes via droplets.
View Article and Find Full Text PDFChlorhexidine-alcohol compared with povidone-iodine-alcohol skin antisepsis protocols in major cardiac surgery: a randomized clinical trial.
Intensive Care Med
December 2024
INSERM U1070 PHAR2, CHU de Poitiers, Université de Poitiers, Service des Urgences Adultes-SAMU 86 Centre 15, Poitiers, France.
Purpose: Whether skin disinfection of the surgical site using chlorhexidine-alcohol is superior to povidone-iodine-alcohol in reducing reoperation and surgical site infection rates after major cardiac surgery remains unclear.
Methods: CLEAN 2 was a multicenter, open-label, randomized, two-arm, assessor-blind, superiority trial conducted in eight French hospitals. We randomly assigned adult patients undergoing major heart or aortic surgery via sternotomy, with or without saphenous vein or radial artery harvesting, to have all surgical sites disinfected with either 2% chlorhexidine-alcohol or 5% povidone-iodine-alcohol.
Effect of Chlorhexidine and Povidone-iodine Mouth Rinses on Corrosion Resistance and Surface Characteristics of Stainless Steel Orthodontic Brackets - An and Study.
Contemp Clin Dent
September 2024
Department of Orthodontics and Dentofacial Orthopedics, Amrita School of Dentistry, Amrita Vishwa Vidyapeetham, Kochi, Kerala, India.
Background: Stainless steel (SS) orthodontic brackets may have varying corrosion resistance when used with mouthwashes during orthodontic treatment. Studying their effects on orthodontic brackets will be beneficial.
Aim: The study's objective was to analyze the surface characteristics of SS orthodontic brackets and their resistance to corrosion, exposed to chlorhexidine and povidone-iodine mouth rinses - an and study.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!