Introduction: Acute radiodermatitis is a significant complication of cancer radiotherapy, and platelet-based therapies are emerging as potential new treatments.
Main Symptoms And Important Clinical Findings: In this report, we present the case of a patient with head and neck cancer undergoing radiotherapy combined with the monoclonal antibody cetuximab. After 4 weeks of this treatment, the patient developed cutaneous radiation dermatitis. Despite receiving standard treatment with corticosteroids and emollient cream, the lesion did not improve.
Main Diagnosis: cutaneous radiation dermatitis on head and neck cancer patient.
Therapeutic Interventions: Topical application of platelet gel was initiated on the wound. From the second week of radiotherapy to the 4th week, homologous platelet-rich plasma was applied on the dermatitis using a bandage, 4 times a day.
Outcomes: The topical treatment with homologous platelet gel resulted in complete healing of the radiodermatitis, including restoration of the epidermis, reepithelialization, and reduction in associated pain.
Conclusion: homologous platelet gel might be an alternative to standard treatment of radiation dermatitis.
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10470763 | PMC |
http://dx.doi.org/10.1097/MD.0000000000034779 | DOI Listing |
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