Humans have innately established close and profound ties with the, and through these relationships shaped many kinds of landscapes. Among these are sacred landscapes, which have drawn the attention of researchers due to their cultural significance. In the field of health geography, large-sized sacred regional landscapes are now the focus of studies for their therapeutic properties. However, few scholars have focused on small sacred landscape systems at the community level (constructed by local communities) or the physical and psycological health benefits that these landscapes offer to the local residents. These small-sized and widespread, but often hidden, sacred landscapes are closely tied to people's daily lives and work. They have evolved and grown over millennia to become critical sociocultural phenomena. This study takes the sacred bao ye landscape of the Dong people of China as the research subject. By adopting the case study approach, field research, semi-structured interviews, and textual analysis, it summarizes the types, geographical distribution, rituals and processes of bao ye as a sacred landscape of the Huanggang village in Guizhou Province, and concludes with an analysis of motivation and health benefits to the bao ye worship. In this paper we argue that bao ye is a sacred landscape system focusing on the healthy development of children, and constitutes a local belief developed in an isolated environment lacking medical resources, which remains in practice. The sacred landscape of bao ye offers a therapeutic environment, providing children with increased opportunities to engage with and build deep connections to nature. Thruogh this process children may develop a bond with nature that inspires them to protect nature on their own accord. We argue that bao ye offers an important case study for understanding the landscape-people-healing interactivity at the community level.
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http://dx.doi.org/10.1016/j.healthplace.2023.103102 | DOI Listing |
EMBO J
January 2025
Telethon Institute of Genetics and Medicine (TIGEM), 80078, Pozzuoli, Italy.
Endoplasmic reticulum (ER) plasticity and ER-phagy are intertwined processes essential for maintaining ER dynamics. We investigated the interplay between two isoforms of the ER-phagy receptor FAM134B in regulating ER remodeling in differentiating myoblasts. During myogenesis, the canonical FAM134B1 is degraded, while its isoform FAM134B2 is transcriptionally upregulated.
View Article and Find Full Text PDFVaccine X
January 2025
Department of Pediatrics, Seoul National University College of Medicine, Republic of Korea.
Vaccination is a cornerstone of public health, preventing infectious diseases with significant contribution to human health. In South Korea, the Korea Expert Committee on Immunization Practices (KECIP) plays a pivotal role in guiding national vaccination policies. In this comprehensive review, we investigated the history, legal basis, operation, and achievements of the KECIP, highlighting its critical role in shaping the country's successful vaccination program.
View Article and Find Full Text PDFNPJ Precis Oncol
December 2024
Department of Woman and Child's Health and Public Health Sciences, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Rome, Italy.
Endometrial cancer (EC) with Mismatch Repair deficiency (MMRd) is characterized by the accumulation of insertions/deletions at microsatellite sites. These mutations lead to the synthesis of frameshift peptides (FSPs) that represent tumor-specific neoantigens (nAg) proved to be shared across patients/tumors with MMRd. In this study, we explored the feasibility of a nAg-based cancer vaccination design in EC with MMRd.
View Article and Find Full Text PDFExp Dermatol
December 2024
Dermatology Unit, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.
Sweet syndrome (SS), originally described as acute febrile neutrophilic dermatosis, is a rare inflammatory skin condition, considered the prototype of neutrophilic dermatoses. It is characterised by the sudden onset of well-defined tender papules, plaques and nodules often accompanied by fever, neutrophilia and elevated markers of inflammation. Several variants have been described both clinically and histopathologically.
View Article and Find Full Text PDFHealthcare (Basel)
November 2024
Sarah Cannon Research Institute, Nashville, TN 37203, USA.
Background: A comparison of the operations of Clinical Cancer Centers and Comprehensive Cancer Centers across Europe provides novel data on the interrelation between different factors in care delivery.
Method: The analysis is based on a survey of key dimensions in care delivery, comparing routine treatment, advanced technology integration, research participation, and innovation adoption across the two types of centers.
Results: Clinical Cancer Centers excel in providing routine cancer treatment through multidisciplinary teams but struggle with advanced technology integration and research participation.
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