Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1183/13993003.01356-2022 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Chymase-1: a "MAST"-er switch in COPD?
Eur Respir J
December 2022
Dept of Molecular Pharmacology, University of Groningen, Groningen, The Netherlands.
The relationship between breast cancer molecular subtypes and mast cell populations in tumor microenvironment.
Virchows Arch
May 2017
Department of Pathomorphology, Jagiellonian University Medical College, ul. Grzegórzecka 16, 31-531, Kraków, Poland.
Mast cells (MCs) are a part of the innate immune system. The MC functions toward cancer are partially based on the release of chymase and tryptase. However, the MC effect on breast cancer is controversial.
View Article and Find Full Text PDFLipid-rich enteral nutrition regulates mucosal mast cell activation via the vagal anti-inflammatory reflex.
Am J Physiol Gastrointest Liver Physiol
September 2013
Dept. of Surgery at Maastricht Univ. Medical Centre+, Universiteitssingel 50, 6229 ER Maastricht, the Netherlands.
Nutritional stimulation of the cholecystokinin-1 receptor (CCK-1R) and nicotinic acetylcholine receptor (nAChR)-mediated vagal reflex was shown to reduce inflammation and preserve intestinal integrity. Mast cells are important early effectors of the innate immune response; therefore modulation of mucosal mast cells is a potential therapeutic target to control the acute inflammatory response in the intestine. The present study investigates intestinal mast cell responsiveness upon nutritional activation of the vagal anti-inflammatory reflex during acute inflammation.
View Article and Find Full Text PDF[Measurement of plasma mast cell carboxypeptidase and chymase levels in children with allergic diseases].
Zhongguo Dang Dai Er Ke Za Zhi
October 2011
Huai'an Women and Children's Health Care Hospital of Jiangsu Province, Huai'an, Jiangsu, China.
Objective: To evaluate the roles of plasma mast cell carboxypeptidase and chymase in the diagnosis of allergic diseases by measuring the contents of both in children.
Methods: A total of 59 children with allergic diseases and 53 healthy children were recruited into the study. Plasma levels of mast cell carboxypeptidase and chymase were measured using ELISA.
Analysis of low abundance membrane-associated proteins from rat pancreatic zymogen granules.
J Proteome Res
October 2010
Department of Cell Biology and Cell Pathology, Philipps University of Marburg, Robert Koch Strasse 6, Marburg, Germany.
Zymogen granules (ZG) are specialized storage organelles in the exocrine pancreas that allow the sorting, packaging, and regulated apical secretion of digestive enzymes. As there is a critical need for further understanding of the key processes in regulated secretion to develop new therapeutic options in medicine, we applied a suborganellar proteomics approach to identify peripheral membrane-associated ZG proteins. We focused on the analysis of a "basic" group (pH range 6.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!