Many soft and biological materials display so-called 'soft glassy' dynamics; their constituents undergo anomalous random motions and complex cooperative rearrangements. A recent simulation model of one soft glassy material, a coarsening foam, suggested that the random motions of its bubbles are due to the system configuration moving over a fractal energy landscape in high-dimensional space. Here we show that the salient geometrical features of such high-dimensional fractal landscapes can be explored and reliably quantified, using empirical trajectory data from many degrees of freedom, in a model-free manner. For a mayonnaise-like dense emulsion, analysis of the observed trajectories of oil droplets quantitatively reproduces the high-dimensional fractal geometry of the configuration path and its associated local energy minima generated using a computational model. That geometry in turn drives the droplets' complex random motion observed in real space. Our results indicate that experimental studies can elucidate whether the similar dynamics in different soft and biological materials may also be due to fractal landscape dynamics.
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http://dx.doi.org/10.1039/d3sm00852e | DOI Listing |
Mol Autism
January 2025
Human Anatomy Department, Nanjing Medical University, No.101 Longmian Avenue, Jiangning District, Nanjing, 211166, Jiangsu, People's Republic of China.
Autism spectrum disorder (ASD) is characterized by difficulties in social interaction, communication challenges, and repetitive behaviors. Despite extensive research, the molecular mechanisms underlying these neurodevelopmental abnormalities remain elusive. We integrated microscale brain gene expression data with macroscale MRI data from 1829 participants, including individuals with ASD and typically developing controls, from the autism brain imaging data exchange I and II.
View Article and Find Full Text PDFJ Environ Manage
January 2025
Key Laboratory of Agricultural Water Resources, Hebei Laboratory of Agricultural Water-Saving, Hebei Key Laboratory of Soil Ecology, Center for Agricultural Resources Research, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, 286 Huaizhong Road, Shijiazhuang, 050021, China. Electronic address:
Knowing the spatial pattern of critical wetland patches has an important significance for the restoration and protection of wetland ecosystems. However, the spatial pattern of critical wetland patches in coastal areas is not well understood, and its influencing factors are also unclear, especially in coastal areas. In this study, landscape indices were used to study the spatial pattern of the wetlands in the Hebei-Tianjin coastal area, North China.
View Article and Find Full Text PDFHuan Jing Ke Xue
November 2024
College of Forestry/Landscape and Art, Jiangxi Agricultural University, Nanchang 330045, China.
Exploring the mechanisms of the impacts of urbanization on soil aggregate stability and soil organic carbon (SOC) content will contribute to improving soil quality in urban greenspaces. Using the built-up area of Nanchang City, Jiangxi Province as a case study, the urbanization intensity was differentiated by impervious rate, and the vegetation characteristics and soil properties of 184 greenspace plots were investigated and determined. Variations in the stability parameters (geometric mean diameter, mean weight diameter, fractal dimension, and unstable aggregate index) and SOC contents across soil aggregate-size fractions (>2, 1-2, 0.
View Article and Find Full Text PDFDiabetologia
January 2025
Unit of β Cell Biology, Diabetes Research Institute, IRCCS San Raffaele Hospital, Milan, Italy.
Aims/hypothesis: Wolfram syndrome 1 (WS1) is an inherited condition mainly manifesting in childhood-onset diabetes mellitus and progressive optic nerve atrophy. The causative gene, WFS1, encodes wolframin, a master regulator of several cellular responses, and the gene's mutations associate with clinical variability. Indeed, nonsense/frameshift variants correlate with more severe symptoms than missense/in-frame variants.
View Article and Find Full Text PDFNat Commun
November 2024
State Key Laboratory of Estuarine and Coastal Research, East China Normal University, Shanghai, China.
Branching networks are key elements in natural landscapes and have attracted sustained research interest across the geosciences and numerous intersecting fields. The prevailing consensus has long held that branching networks are optimized and exhibit fractal properties adhering to power-law scaling relationships. However, tidal networks in coastal wetlands and mudflats exhibit scaling properties that defy conventional power-law descriptions, presenting a longstanding enigma.
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