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DoxyPEP Implementation Preferences for Bacterial STD Prevention Among Gay, Bisexual, and Other Men Who Have Sex with Men Living With and Without HIV in Los Angeles: A Mixed-Methods Approach.
AIDS Patient Care STDS
January 2025
Department of Epidemiology, UCLA Fielding School of Public Health, Los Angeles, California, USA.
Bacterial sexually transmitted diseases (STDs) remain prominent in the United States among gay, bisexual, and other men who have sex with men (GBMSM). Doxycycline for post-exposure prophylaxis (DoxyPEP) is a regimen by which the antibiotic doxycycline is taken after sex to prevent bacterial STDs, such as, chlamydia, gonorrhea, and syphilis. Despite this, this study was conducted because there are a limited number of publications that describe GBMSM's knowledge of, and interest in, taking DoxyPEP and preferences regarding its implementation.
View Article and Find Full Text PDFRelationship between muscle power, muscle volume and limb length in healthy male and female adolescents.
Front Sports Act Living
January 2025
Movement, Sport, Health and Sciences Laboratory (M2S), UFR APS, University of Rennes 2-ENS Cachan, Rennes, France.
Objective: Muscle power is essential for the activities of daily living. Muscle power production depends on numerous factors such as muscle size and length, muscle architecture and fiber type and varies with age during growth. The association between muscle power output during a jump and lower limb muscle volume and length in adolescents is largely unknown.
View Article and Find Full Text PDFThe association of frailty and bedside body composition tools with total body potassium and body cell mass: a pilot study in adults with cirrhosis.
Eur J Clin Nutr
January 2025
Division of Gastroenterology (Liver Unit), Department of Medicine, Faculty of Medicine and Dentistry, University of Alberta, Edmonton, AB, Canada.
The accurate assessment of body composition in cirrhosis is challenging as fluid accumulation affects most techniques. The whole-body counter is a state-of-the-art method that measures total body potassium (TBK) unbiased by fluid, from which body cell mass (BCM) is derived. This pilot study in 20 patients with cirrhosis evaluated bedside tools including the liver frailty index (LFI), bioimpedance analysis-based phase angle, calf circumference (CC), and BMI (body mass index)/edema-adjusted CC, and explored their association with TBK and BCM.
View Article and Find Full Text PDFSexually dimorphic ATF4 expression in the fat confers female stress tolerance in .
bioRxiv
December 2024
Department of Cell Biology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.
Metabolic differences between males and females have been well documented across many species. However, the molecular basis of these differences and how they impact tolerance to nutrient deprivation is still under investigation. In this work, we use to demonstrate that sex-specific differences in fat tissue metabolism are driven, in part, by dimorphic expression of the Integrated Stress Response (ISR) transcription factor, ATF4.
View Article and Find Full Text PDFStroke severity shapes extracellular vesicle profiles and their impact on the cerebral endothelial cells.
J Physiol
January 2025
Vascular Physiology Laboratory, Group of Research and Innovation in Vascular Health, Department of Basic Sciences, Faculty of Basic Sciences, Universidad del Bío-Bío, Chillán, Chile.
Ischaemic stroke is a leading cause of death and disability. Circulating extracellular vesicles (EVs) post-stroke may help brain endothelial cells (BECs) counter ischaemic injury. However data on how EVs from ischaemic stroke patients, considering injury severity, affect these cells are limited.
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