Environmental impacts caused by mining activities (mainly tailings and effluents) are presenting serious challenges for humanity worldwide. In Brazil, clay extraction activities in the Ceramic District of Santa Gertrudes (CDSG) have led to the formation of abandoned drainage wells causing environmental and human health concerns. In the 90's, it was discovered that in one of the production areas, known as the region of the lakes of Santa Gertrudes, several ceramic industries had contaminated lakes created by abandoned clay pits with industrial effluents containing toxic metals. In the present study, analysis of total and dissolved concentrations of Al, Cd, Co, Cu, Mn, Ni, Pb and Zn in the waters of these lakes were combined with the diffusive gradients in thin films (DGT) technique to assess the lability and bioavailability of the target elements, representing one of the first studies to investigate the real environmental impact of contamination caused by ceramic production wastes to an aquatic system. Furthermore, based on the total concentrations and main physicochemical characteristics of each lake, a speciation analysis was performed using the MINTEQ software which data was compared with other surface water systems. The results indicated the presence of metals associated with ceramic residues in total, dissolved and labile fractions. It was verified that Zn, Ni and Cu were the only target metals found in labile form and according to speciation were present in the form of "free" ions, and thus may present risk in terms of bioavailability, although the majority of the total concentrations are within the limits established by the national environmental agency.
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http://dx.doi.org/10.1016/j.chemosphere.2023.139948 | DOI Listing |
Maturitas
November 2024
Disciplina de Ginecologia, Faculdade de Medicina do ABC, Av. Principe de Gales, 821, 2nd floor, Administrative Building, Santo Andre, SP 09060-650, Brazil. Electronic address:
Objective: This study assessed the prevalence and impact of moderate and/or severe vasomotor symptoms and related treatment patterns in midlife women in Brazil.
Study Design: Brazilian women aged 40 to 65 years completed an online survey. The prevalence of moderate to severe vasomotor symptoms was assessed in postmenopausal women who completed a series of questionnaires to elicit responses regarding their treatment patterns and attitudes to treatments.
Int J Environ Res Public Health
October 2023
Pulmonary Division, Heart Institute (InCor), Hospital das Clinicas da Faculdade de Medicina da Universidade de Sao Paulo, Sao Paulo 05403-000, Brazil.
Santa Gertrudes (SG) and Rio Claro (RC), Sao Paulo, Brazil, are located in a ceramic industrial park zone, and their particulate matter with an aerodynamic diameter of less than 10 µm (PM) concentration levels has been among the highest in recently monitored cities in Brazil. Local PM was mostly composed of silica. A cross-sectional study was designed to evaluate the lung functions of public high school students in SG, RC, and São Pedro (SP) (control location), Brazil, in 2018.
View Article and Find Full Text PDFChemosphere
November 2023
Environmental Studies Center (CEA), São Paulo State University, UNESP, Rio Claro, SP, 13506-900, Brazil. Electronic address:
Environmental impacts caused by mining activities (mainly tailings and effluents) are presenting serious challenges for humanity worldwide. In Brazil, clay extraction activities in the Ceramic District of Santa Gertrudes (CDSG) have led to the formation of abandoned drainage wells causing environmental and human health concerns. In the 90's, it was discovered that in one of the production areas, known as the region of the lakes of Santa Gertrudes, several ceramic industries had contaminated lakes created by abandoned clay pits with industrial effluents containing toxic metals.
View Article and Find Full Text PDFExpert Opin Drug Metab Toxicol
February 2015
Federal University of ABC (UFABC), Centre for Natural Sciences and Humanities, Santa Adélia Street, 166, Bangu, Santo André -SP , Brazil.
Introduction: Pharmacokinetics involves the study of absorption, distribution, metabolism, excretion and toxicity of xenobiotics (ADME-Tox). In this sense, the ADME-Tox profile of a bioactive compound can impact its efficacy and safety. Moreover, efficacy and safety were considered some of the major causes of clinical failures in the development of new chemical entities.
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