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Effects of Extracted Pulse Proteins on Lipid Targets for Cardiovascular Risk Reduction: Systematic Review and Meta-Analysis of Randomized Controlled Trials.
Nutrients
November 2024
Department of Nutritional Sciences, Temerty Faculty of Medicine, University of Toronto, Toronto, ON M5S 1A8, Canada.
Background: Many clinical practice guidelines recommend dietary pulses for the prevention and management of cardiovascular disease and diabetes. The impact of extracted pulse proteins remains unclear. We therefore conducted a systematic review and meta-analysis of randomized controlled trials of the effect of extracted pulse proteins on therapeutic lipid targets.
View Article and Find Full Text PDFThis essay examines the impact of linguistic choices on the perception and regulation of assisted dying, particularly in Canada. It argues that euphemistic terms like "medical assistance in dying" and its acronym, "MAID," serve to normalize the practice, potentially obscuring its moral gravity. This contrasts with what is seen in Belgium and the Netherlands, where terms like "euthanasia" are used, as well as in France and the United Kingdom, where terminology remains divisive and contested.
View Article and Find Full Text PDFEffect of Soy Isoflavones on Measures of Estrogenicity: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.
Adv Nutr
January 2025
Department of Nutritional Sciences, Temerty Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada; Toronto 3D Knowledge Synthesis and Clinical Trials Unit, Clinical Nutrition and Risk Factor Modification Centre, St. Michael's Hospital, Toronto, Ontario, Canada; Li Ka Shing Knowledge Institute, St. Michael's Hospital, Toronto, Ontario, Canada. Electronic address:
Article Synopsis
- There is a growing push for increased plant food consumption, particularly soy foods, which have potential health benefits for women, despite ongoing controversies regarding their effects.
- A systematic review and meta-analysis of 40 randomized trials involving over 3,000 postmenopausal women were conducted to assess the impacts of soy isoflavones on various estrogen-related measures.
- The results showed no significant effects of soy isoflavones on endometrial thickness, vaginal maturation, follicle-stimulating hormone, or estradiol levels, indicating that they may function as selective estrogen receptor modulators rather than acting like estrogen itself.
The evolving legal landscape associated with medical assistance in dying (MAiD) may pose significant challenges for hospice and palliative care professionals. In the United States, 10 states and 1 jurisdiction have passed legislation allowing MAiD. National organizations, such as the Hospice and Palliative Nurses Association, have created position statements to serve as guides to care.
View Article and Find Full Text PDFPublic Deliberation for Ethically Complex Policies: The Case of Medical Assistance in Dying in Canada.
Healthc Policy
September 2024
Professor, Department of Health Research Methods, Evidence and Impact, Centre for Health Economics and Policy Analysis, McMaster University, Hamilton, ON.
Almost 50,000 people in Canada have had a medically assisted death since federal legislation was passed in 2016. Still, the debate about the permissibility of medical assistance in dying (MAiD) continues to rage. The central role of shared values and ethics in public policy making emphasizes the importance of engaging the public, particularly around heavily value-laden issues such as MAiD.
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