The emerging role of IL-38 in diseases: A comprehensive review.

Immun Inflamm Dis

Center of Forensic Expertise, Affiliated Hospital of Zunyi Medical University, Zunyi, Guizhou, China.

Published: August 2023

Introduction: Interleukin-38 (IL-38) is a new type of anti-inflammatory cytokine, which is mainly expressed in the immunity-related organs and is involved in various diseases including cardiovascular and cerebrovascular diseases, lung diseases, viral infectious diseases and autoimmune diseases.

Aim: This review aims to detail the biological function, receptors and signaling of IL-38, which highlights its therapeutic potential in related diseases.

Conclusion: This article provides a comprehensive review of the association between interleukin-38 and related diseases, using interleukin-38 as a keyword and searching the relevant literature through Pubmed and Web of science up to July 2023.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10461426PMC
http://dx.doi.org/10.1002/iid3.991DOI Listing

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