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Differences in Sensorimotor Integration, Cervical Sensorimotor Control, and Cognitive-Motor Dual Tasking Costs in Chronic Non-Specific Neck Pain Patients with High vs. Low Catastrophizing Tendencies Compared to Healthy Controls.
Behav Brain Res
January 2025
CBP Nonprofit (a spine research foundation), Eagle, ID 83616, USA.
Chronic non-specific neck pain (CNSNP) is a common condition and its relationship to the pain catastrophizing construct in terms of sensorimotor functions and dual task performance is not fully understood. We aimed to investigate the differences in sensorimotor integration, cervical sensorimotor control, and cognitive-motor dual tasking abilities between CNSNP patients (> 3 months) with high versus low catastrophizing tendencies and healthy controls. Ninety participants were recruited, 30 asymptomatic controls, and 60 patients with CNSNP; 30 scoring high (> 75 percentile) and 30 scoring low (< 25th percentile) on the pain catastrophizing scale (PCS).
View Article and Find Full Text PDFIntroduction: Mu-opioid receptors (MORs) are G-coupled protein receptors with a high affinity for both endogenous and exogenous opioids. MORs are widely expressed in the central nervous system (CNS), peripheral organs, and the immune system. They mediate pain and reward and have been implicated in the pathophysiology of opioid, cocaine, and other substance use disorders.
View Article and Find Full Text PDFAltered brain functional connectivity in patients with tension-type headache.
Headache
January 2025
School of Psychology, Zhejiang Normal University, Jinhua, China.
Objective: To evaluate whether patients with tension-type headache (TTH) exhibit abnormal brain functional connectivity compared to healthy controls.
Background: TTH is one of the most prevalent headache disorders throughout the world. The present study delves into brain functional connectivity in patients with TTH to enhance the understanding of its underlying pathophysiology.
Abnormal functional hubs in migraine patients: a resting-state MRI analysis about voxel-wise degree centrality.
J Oral Facial Pain Headache
March 2024
Department of Acupuncture and Moxibustion, Dongzhimen Hospital Beijing University of Chinese Medicine, 100700 Beijing, China.
The purpose was to explore the spatial centrality of the whole brain functional network related to migraine and to investigate the potential functional hubs associated with migraine. 32 migraine patients and 55 healthy controls were recruited and they received resting-state functional magnetic resonance imaging voluntarily. Voxel-wise Degree Centrality (DC) was measured across the whole brain, and group differences in DC were compared.
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