AI Article Synopsis
- Potato and tomato crops are impacted by late blight from the pathogen Phytophthora infestans, while the related plant Solanum americanum shows resistance to this disease.
- Researchers sequenced the genomes of four S. americanum accessions, analyzed 52 more for immune receptor genes (NLR genes), and tested their responses to 315P. infestans RXLR effectors.
- The study identified three specific genes (Rpi-amr4, R02860, and R04373) that can recognize certain blight-causing effectors, providing resources to help develop potatoes with better resistance to late blight and potentially other crop diseases.
Article Abstract
Potato (Solanum tuberosum) and tomato (Solanum lycopersicon) crops suffer severe losses to late blight caused by the oomycete pathogen Phytophthora infestans. Solanum americanum, a relative of potato and tomato, is globally distributed and most accessions are highly blight resistant. We generated high-quality reference genomes of four S. americanum accessions, resequenced 52 accessions, and defined a pan-NLRome of S. americanum immune receptor genes. We further screened for variation in recognition of 315P. infestans RXLR effectors in 52 S. americanum accessions. Using these genomic and phenotypic data, we cloned three NLR-encoding genes, Rpi-amr4, R02860 and R04373, that recognize cognate P. infestans RXLR effectors PITG_22825 (AVRamr4), PITG_02860 and PITG_04373. These genomic resources and methodologies will support efforts to engineer potatoes with durable late blight resistance and can be applied to diseases of other crops.
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Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10484786 | PMC |
| http://dx.doi.org/10.1038/s41588-023-01486-9 | DOI Listing |
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