Journal of the Formosan Medical Association = Taiwan yi zhi

0929-664612332024MarJournal of the Formosan Medical Association = Taiwan yi zhiJ Formos Med AssocCT findings of 144 in-hospital patients with influenza pneumonia: A retrospective analysis.381389381-38910.1016/j.jfma.2023.08.022S0929-6646(23)00336-4Patients with influenza infection during their period of admission may have worse computed tomography (CT) manifestation according to the clinical status. This study aimed to evaluate the CT findings of in-hospital patients due to clinically significant influenza pneumonia with correlation of clinical presentations.In this retrospective, single center case series, 144 patients were included. All in-hospital patients were confirmed influenza infection and underwent CT scan. These patients were divided into three groups according to the clinical status of the most significant management: (1) without endotracheal tube and mechanical ventilator (ETTMV) or extracorporeal membrane oxygenation (ECMO); (2) with ETTMV; (3) with ETTMV and ECMO. Pulmonary opacities were scored according to extent. Spearman rank correlation analysis was used to evaluate the correlation between clinical parameters and CT scores.The predominant CT manifestation of influenza infection was mixed ground-glass opacity (GGO) and consolidation with both lung involvement. The CT scores were all reach significant difference among all three groups (8.73 ± 6.29 vs 12.49 ± 6.69 vs 18.94 ± 4.57, p < 0.05). The chest CT score was correlated with age, mortality, and intensive care unit (ICU) days (all p values were less than 0.05). In addition, the CT score was correlated with peak lactate dehydrogenase (LDH) level and peak C-reactive protein (CRP) level (all p values were less than 0.05). Concomitant bacterial infection had higher CT score than primary influenza pneumonia (13.02 ± 7.27 vs 8.95 ± 5.99, p < 0.05).Thin-section chest CT scores correlated with clinical and laboratory parameters in in-hospital patients with influenza pneumonia.Copyright © 2023. Published by Elsevier B.V.KangVictor Jing-WeiVJDepartment of Medical Imaging, National Taiwan University, Taipei, Taiwan. Electronic address: cavotta1020@gmail.com.HuangYu-SenYSDepartment of Medical Imaging, National Taiwan University, Taipei, Taiwan. Electronic address: yusen0814@gmail.com.ChenMei-ChiMCDepartment of Medical Imaging, National Taiwan University, Taipei, Taiwan. Electronic address: chantecaillee@gmail.com.ChiangPin-YiPYDepartment of Medical Imaging, National Taiwan University, Taipei, Taiwan. Electronic address: u9310378@hotmail.com.ShengWang-HueiWHDivision of Infectious Diseases, Department of Internal Medicine, National Taiwan University, Taipei, Taiwan; Department of Internal Medicine, National Taiwan University College of Medicine, Taiwan. Electronic address: whsheng@ntu.edu.tw.WangHao-ChienHCDepartment of Internal Medicine, National Taiwan University College of Medicine, Taiwan; Division of Chest Medicine, Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan. Electronic address: haochienwang@gmail.com.WangTeh-ChenTCDepartment Medical Imaging, Taipei City Hospital Yang-Ming Branch, Taipei, Taiwan. Electronic address: tehchenwang@gmail.com.ChangYeun-ChungYCDepartment of Medical Imaging, National Taiwan University, Taipei, Taiwan; Department of Radiology, National Taiwan University College of Medicine, Taipei, Taiwan. Electronic address: ycc5566@ntu.edu.tw.engJournal Article20230826